PCDH12 (protocadherin 12)

2014-11-01  

Identity

HGNC
LOCATION
5q31.3
LOCUSID
ALIAS
DMJDS1,VE-cadherin-2,VECAD2
FUSION GENES

Other Information

Locus ID:

NCBI: 51294
MIM: 605622
HGNC: 8657
Ensembl: ENSG00000113555

Variants:

dbSNP: 51294
ClinVar: 51294
TCGA: ENSG00000113555
COSMIC: PCDH12

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000113555ENST00000231484Q9NPG4
ENSG00000113555ENST00000510041E5RJD4

Expression (GTEx)

0
5
10
15
20
25
30

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
375366612023Asynchronous presentation and evolution of homozygous PCDH12 variant-induced exudative retinopathy in two siblings.0
375366612023Asynchronous presentation and evolution of homozygous PCDH12 variant-induced exudative retinopathy in two siblings.0
347738252022The phenotypic spectrum of PCDH12 associated disorders - Five new cases and review of the literature.4
349293932022PCDH12 variants are associated with basal ganglia anomalies and exudative vitreoretinopathy.2
347738252022The phenotypic spectrum of PCDH12 associated disorders - Five new cases and review of the literature.4
349293932022PCDH12 variants are associated with basal ganglia anomalies and exudative vitreoretinopathy.2
335277192021Ophthalmic phenotypes associated with biallelic loss-of-function PCDH12 variants.3
335277192021Ophthalmic phenotypes associated with biallelic loss-of-function PCDH12 variants.3
304594662019Homozygous PCDH12 variants result in phenotype of cerebellar ataxia, dystonia, retinopathy, and dysmorphism.4
304594662019Homozygous PCDH12 variants result in phenotype of cerebellar ataxia, dystonia, retinopathy, and dysmorphism.4
299041132018A commentary on a case of new PCDH12 gene variants presented as dyskinetic cerebral palsy with epilepsy.0
301784642018Loss of Protocadherin-12 Leads to Diencephalic-Mesencephalic Junction Dysplasia Syndrome.12
299041132018A commentary on a case of new PCDH12 gene variants presented as dyskinetic cerebral palsy with epilepsy.0
301784642018Loss of Protocadherin-12 Leads to Diencephalic-Mesencephalic Junction Dysplasia Syndrome.12
271646832016Loss of function of PCDH12 underlies recessive microcephaly mimicking intrauterine infection.13

Citation

Dessen P

PCDH12 (protocadherin 12)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/71696/pcdh12-(protocadherin-12)