PCSK1N (proprotein convertase subtilisin/kexin type 1 inhibitor)

2014-11-01  

Identity

HGNC
LOCATION
Xp11.23
LOCUSID
ALIAS
BigLEN,PEN,PROSAAS,SAAS,SCG8,SgVIII

Other Information

Locus ID:

NCBI: 27344
MIM: 300399
HGNC: 17301
Ensembl: ENSG00000102109

Variants:

dbSNP: 27344
ClinVar: 27344
TCGA: ENSG00000102109
COSMIC: PCSK1N

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000102109ENST00000218230Q9UHG2

Expression (GTEx)

0
500
1000
1500
2000

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
274579572016The neural chaperone proSAAS blocks α-synuclein fibrillation and neurotoxicity.27
274579572016The neural chaperone proSAAS blocks α-synuclein fibrillation and neurotoxicity.27
226951732013Frequencies of obesity susceptibility alleles among ethnically and racially diverse bariatric patient populations.5
226951732013Frequencies of obesity susceptibility alleles among ethnically and racially diverse bariatric patient populations.5
189483942009Identification of proSAAS homologs in lower vertebrates: conservation of hydrophobic helices and convertase-inhibiting sequences.13
189483942009Identification of proSAAS homologs in lower vertebrates: conservation of hydrophobic helices and convertase-inhibiting sequences.13
147468992004A human granin-like neuroendocrine peptide precursor (proSAAS) immunoreactivity in tau inclusions of Alzheimer's disease and parkinsonism-dementia complex on Guam.15
147468992004A human granin-like neuroendocrine peptide precursor (proSAAS) immunoreactivity in tau inclusions of Alzheimer's disease and parkinsonism-dementia complex on Guam.15
117195032002Functional characterization of ProSAAS: similarities and differences with 7B2.16
117195032002Functional characterization of ProSAAS: similarities and differences with 7B2.16

Citation

Dessen P

PCSK1N (proprotein convertase subtilisin/kexin type 1 inhibitor)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/71775/pcsk1n-(proprotein-convertase-subtilisin-kexin-type-1-inhibitor)