Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 201626
MIM: 616519
HGNC: 25386
Ensembl: ENSG00000174840
Variants:
dbSNP: 201626
ClinVar: 201626
TCGA: ENSG00000174840
COSMIC: PDE12
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000174840 | ENST00000311180 | Q6L8Q7 |
| ENSG00000174840 | ENST00000487257 | F6T1Q0 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38325798 | 2024 | PDE12 disrupts mitochondrial oxidative phosphorylation and mediates mitochondrial dysfunction to induce oral mucosal epithelial barrier damage in oral submucous fibrosis. | 0 |
| 38325798 | 2024 | PDE12 disrupts mitochondrial oxidative phosphorylation and mediates mitochondrial dysfunction to induce oral mucosal epithelial barrier damage in oral submucous fibrosis. | 0 |
| 36307540 | 2022 | PDE12 in type 1 diabetes. | 1 |
| 36307540 | 2022 | PDE12 in type 1 diabetes. | 1 |
| 26055709 | 2015 | The Role of Phosphodiesterase 12 (PDE12) as a Negative Regulator of the Innate Immune Response and the Discovery of Antiviral Inhibitors. | 31 |
| 26055709 | 2015 | The Role of Phosphodiesterase 12 (PDE12) as a Negative Regulator of the Innate Immune Response and the Discovery of Antiviral Inhibitors. | 31 |
| 21245038 | 2011 | Human 2'-phosphodiesterase localizes to the mitochondrial matrix with a putative function in mitochondrial RNA turnover. | 23 |
| 21666256 | 2011 | PDE12 removes mitochondrial RNA poly(A) tails and controls translation in human mitochondria. | 57 |
| 21245038 | 2011 | Human 2'-phosphodiesterase localizes to the mitochondrial matrix with a putative function in mitochondrial RNA turnover. | 23 |
| 21666256 | 2011 | PDE12 removes mitochondrial RNA poly(A) tails and controls translation in human mitochondria. | 57 |
| 20445249 | 2010 | Crystallization and preliminary X-ray crystallographic analysis of human phosphodiesterase 12. | 1 |
| 20877624 | 2010 | Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. | 20 |
| 20445249 | 2010 | Crystallization and preliminary X-ray crystallographic analysis of human phosphodiesterase 12. | 1 |
| 20877624 | 2010 | Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. | 20 |
Citation
Dessen P
PDE12 (phosphodiesterase 12)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/71789/
