Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 118987
MIM: 614235
HGNC: 26974
Ensembl: ENSG00000165650
Variants:
dbSNP: 118987
ClinVar: 118987
TCGA: ENSG00000165650
COSMIC: PDZD8
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000165650 | ENST00000334464 | Q8NEN9 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35227461 | 2022 | PDZD8 Disruption Causes Cognitive Impairment in Humans, Mice, and Fruit Flies. | 10 |
| 35227461 | 2022 | PDZD8 Disruption Causes Cognitive Impairment in Humans, Mice, and Fruit Flies. | 10 |
| 32917905 | 2020 | Protrudin and PDZD8 contribute to neuronal integrity by promoting lipid extraction required for endosome maturation. | 36 |
| 32917905 | 2020 | Protrudin and PDZD8 contribute to neuronal integrity by promoting lipid extraction required for endosome maturation. | 36 |
| 31636202 | 2019 | PDZD8 mediates a Rab7-dependent interaction of the ER with late endosomes and lysosomes. | 36 |
| 31636202 | 2019 | PDZD8 mediates a Rab7-dependent interaction of the ER with late endosomes and lysosomes. | 36 |
| 25771112 | 2015 | Efficient human immunodeficiency virus (HIV-1) infection of cells lacking PDZD8. | 14 |
| 25771112 | 2015 | Efficient human immunodeficiency virus (HIV-1) infection of cells lacking PDZD8. | 14 |
| 24554657 | 2014 | Contribution of PDZD8 to stabilization of the human immunodeficiency virus type 1 capsid. | 22 |
| 24554657 | 2014 | Contribution of PDZD8 to stabilization of the human immunodeficiency virus type 1 capsid. | 22 |
| 21549406 | 2011 | PDZD8 is a novel moesin-interacting cytoskeletal regulatory protein that suppresses infection by herpes simplex virus type 1. | 16 |
| 21549406 | 2011 | PDZD8 is a novel moesin-interacting cytoskeletal regulatory protein that suppresses infection by herpes simplex virus type 1. | 16 |
| 20573829 | 2010 | PDZD8 is a novel Gag-interacting factor that promotes retroviral infection. | 19 |
| 20573829 | 2010 | PDZD8 is a novel Gag-interacting factor that promotes retroviral infection. | 19 |
| 16385451 | 2006 | A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. | 83 |
Citation
Dessen P
PDZD8 (PDZ domain containing 8)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/71818/pdzd8-(pdz-domain-containing-8)
