PECR (peroxisomal trans-2-enoyl-CoA reductase)

2014-11-01

Identity

HGNC

PECR

LOCATION

2q35

LOCUSID

55825

ALIAS

DCRRP,HPDHASE,HSA250303,PVIARL,SDR29C1,TERP

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 55825
MIM: 605843
HGNC: 18281
Ensembl: ENSG00000115425

Variants:

dbSNP: 55825
ClinVar: 55825
TCGA: ENSG00000115425
COSMIC: PECR

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000115425	ENST00000265322	Q9BY49
ENSG00000115425	ENST00000442122	B4DJS2

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Biosynthesis of unsaturated fatty acids	KEGG	ko01040
Biosynthesis of unsaturated fatty acids	KEGG	hsa01040
Fatty acid metabolism	KEGG	hsa01212
Fatty acid metabolism	KEGG	ko01212
Metabolism	REACTOME	R-HSA-1430728
Metabolism of lipids and lipoproteins	REACTOME	R-HSA-556833
Peroxisomal lipid metabolism	REACTOME	R-HSA-390918
Peroxisome	KEGG	ko04146
Peroxisome	KEGG	hsa04146

Previous1Next

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
16546181	2006	Peroxisomal trans-2-enoyl-CoA reductase is involved in phytol degradation.	9
16546181	2006	Peroxisomal trans-2-enoyl-CoA reductase is involved in phytol degradation.	9
20463177	2010	Multistudy fine mapping of chromosome 2q identifies XRCC5 as a chronic obstructive pulmonary disease susceptibility gene.	15
20463177	2010	Multistudy fine mapping of chromosome 2q identifies XRCC5 as a chronic obstructive pulmonary disease susceptibility gene.	15
22745130	2012	Studies of human 2,4-dienoyl CoA reductase shed new light on peroxisomal β-oxidation of unsaturated fatty acids.	9
22745130	2012	Studies of human 2,4-dienoyl CoA reductase shed new light on peroxisomal β-oxidation of unsaturated fatty acids.	9
33482198	2021	Trans-2-enoyl-CoA reductase limits Ca(2+) accumulation in the endoplasmic reticulum by inhibiting the Ca(2+) pump SERCA2b.	1
33482198	2021	Trans-2-enoyl-CoA reductase limits Ca(2+) accumulation in the endoplasmic reticulum by inhibiting the Ca(2+) pump SERCA2b.	1

Previous1Next

Citation

Dessen P

PECR (peroxisomal trans-2-enoyl-CoA reductase)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/71823