Identity
HGNC
LOCATION
3q26.33
LOCUSID
ALIAS
PEX5R,PEX5RP,PXR2,PXR2B,TRIP8b
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 51555
MIM: 611058
HGNC: 30024
Ensembl: ENSG00000114757
Variants:
dbSNP: 51555
ClinVar: 51555
TCGA: ENSG00000114757
COSMIC: PEX5L
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Peroxisome | KEGG | ko04146 |
| Peroxisome | KEGG | hsa04146 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35502931 | 2022 | Genetic variants in DDO and PEX5L in peroxisome-related pathways predict non-small cell lung cancer survival. | 1 |
| 35502931 | 2022 | Genetic variants in DDO and PEX5L in peroxisome-related pathways predict non-small cell lung cancer survival. | 1 |
| 28864772 | 2017 | Mechanism for the inhibition of the cAMP dependence of HCN ion channels by the auxiliary subunit TRIP8b. | 20 |
| 28887304 | 2017 | Allostery between two binding sites in the ion channel subunit TRIP8b confers binding specificity to HCN channels. | 9 |
| 28864772 | 2017 | Mechanism for the inhibition of the cAMP dependence of HCN ion channels by the auxiliary subunit TRIP8b. | 20 |
| 28887304 | 2017 | Allostery between two binding sites in the ion channel subunit TRIP8b confers binding specificity to HCN channels. | 9 |
| 25538232 | 2015 | Mechanistic insights into PTS2-mediated peroxisomal protein import: the co-receptor PEX5L drastically increases the interaction strength between the cargo protein and the receptor PEX7. | 17 |
| 25538232 | 2015 | Mechanistic insights into PTS2-mediated peroxisomal protein import: the co-receptor PEX5L drastically increases the interaction strength between the cargo protein and the receptor PEX7. | 17 |
| 24451387 | 2014 | Nedd4-2 regulates surface expression and may affect N-glycosylation of hyperpolarization-activated cyclic nucleotide-gated (HCN)-1 channels. | 8 |
| 25197093 | 2014 | Structural basis for the mutual antagonism of cAMP and TRIP8b in regulating HCN channel function. | 52 |
| 24451387 | 2014 | Nedd4-2 regulates surface expression and may affect N-glycosylation of hyperpolarization-activated cyclic nucleotide-gated (HCN)-1 channels. | 8 |
| 25197093 | 2014 | Structural basis for the mutual antagonism of cAMP and TRIP8b in regulating HCN channel function. | 52 |
| 22550182 | 2012 | Structure and stoichiometry of an accessory subunit TRIP8b interaction with hyperpolarization-activated cyclic nucleotide-gated channels. | 33 |
| 23077068 | 2012 | TRIP8b-independent trafficking and plasticity of adult cortical presynaptic HCN1 channels. | 24 |
| 22550182 | 2012 | Structure and stoichiometry of an accessory subunit TRIP8b interaction with hyperpolarization-activated cyclic nucleotide-gated channels. | 33 |
Citation
Dessen P
PEX5L (peroxisomal biogenesis factor 5 like)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/71843/pex5l-(peroxisomal-biogenesis-factor-5-like)
