PGLYRP2 (peptidoglycan recognition protein 2)

2014-11-01  

Identity

HGNC
PGLYRP2
LOCATION
19p13.12
LOCUSID
114770
ALIAS
HMFT0141,PGLYRPL,PGRP-L,PGRPL,TAGL-like,tagL,tagL-alpha,tagl-beta

Other Information

Locus ID:

NCBI: 114770
MIM: 608199
HGNC: 30013
Ensembl: ENSG00000161031

Variants:

dbSNP: 114770
ClinVar: 114770
TCGA: ENSG00000161031
COSMIC: PGLYRP2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000161031ENST00000292609Q96PD5
ENSG00000161031ENST00000340880Q96PD5
ENSG00000161031ENST00000594637M0QYW3
ENSG00000161031ENST00000601792M0R2W8

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Antimicrobial peptidesREACTOMER-HSA-6803157

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
352188882022Association of PGLYRP2 gene polymorphism and sporadic Parkinson's disease in northern Chinese Han population.2
352188882022Association of PGLYRP2 gene polymorphism and sporadic Parkinson's disease in northern Chinese Han population.2
334276212021Antibody to peptidoglycan recognition protein (PGLYRP)-2 as a novel biomarker in rheumatoid arthritis.4
344619242021PGLYRP2 as a novel biomarker for the activity and lipid metabolism of systemic lupus erythematosus.4
334276212021Antibody to peptidoglycan recognition protein (PGLYRP)-2 as a novel biomarker in rheumatoid arthritis.4
344619242021PGLYRP2 as a novel biomarker for the activity and lipid metabolism of systemic lupus erythematosus.4
314795232020Tumor-Derived Peptidoglycan Recognition Protein 2 Predicts Survival and Antitumor Immune Responses in Hepatocellular Carcinoma.16
329670432020Serum sCD14, PGLYRP2 and FGA as potential biomarkers for multidrug-resistant tuberculosis based on data-independent acquisition and targeted proteomics.11
314795232020Tumor-Derived Peptidoglycan Recognition Protein 2 Predicts Survival and Antitumor Immune Responses in Hepatocellular Carcinoma.16
329670432020Serum sCD14, PGLYRP2 and FGA as potential biomarkers for multidrug-resistant tuberculosis based on data-independent acquisition and targeted proteomics.11
299149272018Regulation of the Peptidoglycan Amidase PGLYRP2 in Epithelial Cells by Interleukin-36γ.7
299149272018Regulation of the Peptidoglycan Amidase PGLYRP2 in Epithelial Cells by Interleukin-36γ.7
260390762015A Novel Innate Response of Human Corneal Epithelium to Heat-killed Candida albicans by Producing Peptidoglycan Recognition Proteins.10
260390762015A Novel Innate Response of Human Corneal Epithelium to Heat-killed Candida albicans by Producing Peptidoglycan Recognition Proteins.10
248381822014Peptidoglycan recognition protein genes and risk of Parkinson's disease.16

Citation

Dessen P

PGLYRP2 (peptidoglycan recognition protein 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/71864/pglyrp2-(peptidoglycan-recognition-protein-2)