Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 57115
MIM: 608198
HGNC: 30015
Ensembl: ENSG00000163218
Variants:
dbSNP: 57115
ClinVar: 57115
TCGA: ENSG00000163218
COSMIC: PGLYRP4
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000163218 | ENST00000359650 | Q96LB8 |
| ENSG00000163218 | ENST00000368739 | Q96LB8 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Immune System | REACTOME | R-HSA-168256 |
| Innate Immune System | REACTOME | R-HSA-168249 |
| Antimicrobial peptides | REACTOME | R-HSA-6803157 |
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA164713366 | Tumor necrosis factor alpha (TNF-alpha) inhibitors | Chemical | ClinicalAnnotation | associated | PD | 27670765 | |
| PA445451 | Psoriasis | Disease | ClinicalAnnotation | associated | PD | 27670765 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 31616404 | 2019 | Peptidoglycan Recognition Protein 4 Limits Bacterial Clearance and Inflammation in Lungs by Control of the Gut Microbiota. | 10 |
| 31616404 | 2019 | Peptidoglycan Recognition Protein 4 Limits Bacterial Clearance and Inflammation in Lungs by Control of the Gut Microbiota. | 10 |
| 26039076 | 2015 | A Novel Innate Response of Human Corneal Epithelium to Heat-killed Candida albicans by Producing Peptidoglycan Recognition Proteins. | 10 |
| 26039076 | 2015 | A Novel Innate Response of Human Corneal Epithelium to Heat-killed Candida albicans by Producing Peptidoglycan Recognition Proteins. | 10 |
| 24838182 | 2014 | Peptidoglycan recognition protein genes and risk of Parkinson's disease. | 16 |
| 24838182 | 2014 | Peptidoglycan recognition protein genes and risk of Parkinson's disease. | 16 |
| 20237496 | 2010 | New genetic associations detected in a host response study to hepatitis B vaccine. | 37 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 20237496 | 2010 | New genetic associations detected in a host response study to hepatitis B vaccine. | 37 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 16354652 | 2006 | Peptidoglycan recognition proteins are a new class of human bactericidal proteins. | 76 |
| 16362825 | 2006 | Peptidoglycan recognition proteins Pglyrp3 and Pglyrp4 are encoded from the epidermal differentiation complex and are candidate genes for the Psors4 locus on chromosome 1q21. | 13 |
| 16354652 | 2006 | Peptidoglycan recognition proteins are a new class of human bactericidal proteins. | 76 |
| 16362825 | 2006 | Peptidoglycan recognition proteins Pglyrp3 and Pglyrp4 are encoded from the epidermal differentiation complex and are candidate genes for the Psors4 locus on chromosome 1q21. | 13 |
Citation
Dessen P
PGLYRP4 (peptidoglycan recognition protein 4)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/71866/pglyrp4-(peptidoglycan-recognition-protein-4)
