Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10531
MIM: 618211
HGNC: 17663
Ensembl: ENSG00000107959
Variants:
dbSNP: 10531
ClinVar: 10531
TCGA: ENSG00000107959
COSMIC: PITRM1
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35751131 | 2023 | PITRM1 interaction studies with amyloidogenic nonapeptide mutants of familial Alzheimer's disease. | 0 |
| 35751131 | 2023 | PITRM1 interaction studies with amyloidogenic nonapeptide mutants of familial Alzheimer's disease. | 0 |
| 32491259 | 2021 | Functional coupling of presequence processing and degradation in human mitochondria. | 8 |
| 32632204 | 2021 | Loss of function of the mitochondrial peptidase PITRM1 induces proteotoxic stress and Alzheimer's disease-like pathology in human cerebral organoids. | 56 |
| 33951271 | 2021 | Gain of PITRM1 peptidase in cortical neurons affords protection of mitochondrial and synaptic function in an advanced age mouse model of Alzheimer's disease. | 4 |
| 32491259 | 2021 | Functional coupling of presequence processing and degradation in human mitochondria. | 8 |
| 32632204 | 2021 | Loss of function of the mitochondrial peptidase PITRM1 induces proteotoxic stress and Alzheimer's disease-like pathology in human cerebral organoids. | 56 |
| 33951271 | 2021 | Gain of PITRM1 peptidase in cortical neurons affords protection of mitochondrial and synaptic function in an advanced age mouse model of Alzheimer's disease. | 4 |
| 32857715 | 2020 | Expression of IDE and PITRM1 genes in ERN1 knockdown U87 glioma cells: effect of hypoxia and glucose deprivation. | 4 |
| 32857715 | 2020 | Expression of IDE and PITRM1 genes in ERN1 knockdown U87 glioma cells: effect of hypoxia and glucose deprivation. | 4 |
| 29216386 | 2019 | An Exome-Wide Association Study Identifies New Susceptibility Loci for Age of Smoking Initiation in African- and European-American Populations. | 4 |
| 29216386 | 2019 | An Exome-Wide Association Study Identifies New Susceptibility Loci for Age of Smoking Initiation in African- and European-American Populations. | 4 |
| 29383861 | 2018 | Functional requirement for human pitrilysin metallopeptidase 1 arginine 183, mutated in amyloidogenic neuropathy. | 3 |
| 29764912 | 2018 | Mitochondrial PITRM1 peptidase loss-of-function in childhood cerebellar atrophy. | 19 |
| 29383861 | 2018 | Functional requirement for human pitrilysin metallopeptidase 1 arginine 183, mutated in amyloidogenic neuropathy. | 3 |
Citation
Dessen P
PITRM1 (pitrilysin metallopeptidase 1)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/71932/pitrm1-(pitrilysin-metallopeptidase-1)
