Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 64219
MIM: 300420
HGNC: 16648
Ensembl: ENSG00000181191
Variants:
dbSNP: 64219
ClinVar: 64219
TCGA: ENSG00000181191
COSMIC: PJA1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38906860 | 2024 | PJA1-mediated suppression of pyroptosis as a driver of docetaxel resistance in nasopharyngeal carcinoma. | 0 |
| 38906860 | 2024 | PJA1-mediated suppression of pyroptosis as a driver of docetaxel resistance in nasopharyngeal carcinoma. | 0 |
| 33839405 | 2021 | E3 ubiquitin ligase PJA1 regulates lung adenocarcinoma apoptosis and invasion through promoting FOXR2 degradation. | 5 |
| 34161122 | 2021 | Praja1 ubiquitin ligase facilitates degradation of polyglutamine proteins and suppresses polyglutamine-mediated toxicity. | 7 |
| 33839405 | 2021 | E3 ubiquitin ligase PJA1 regulates lung adenocarcinoma apoptosis and invasion through promoting FOXR2 degradation. | 5 |
| 34161122 | 2021 | Praja1 ubiquitin ligase facilitates degradation of polyglutamine proteins and suppresses polyglutamine-mediated toxicity. | 7 |
| 32127355 | 2020 | Targeting the E3 Ubiquitin Ligase PJA1 Enhances Tumor-Suppressing TGFβ Signaling. | 9 |
| 32530565 | 2020 | A recurrent PJA1 variant in trigonocephaly and neurodevelopmental disorders. | 9 |
| 32686212 | 2020 | Praja1 RING-finger E3 ubiquitin ligase suppresses neuronal cytoplasmic TDP-43 aggregate formation. | 13 |
| 32127355 | 2020 | Targeting the E3 Ubiquitin Ligase PJA1 Enhances Tumor-Suppressing TGFβ Signaling. | 9 |
| 32530565 | 2020 | A recurrent PJA1 variant in trigonocephaly and neurodevelopmental disorders. | 9 |
| 32686212 | 2020 | Praja1 RING-finger E3 ubiquitin ligase suppresses neuronal cytoplasmic TDP-43 aggregate formation. | 13 |
| 21461837 | 2011 | Protein microarrays for the identification of praja1 e3 ubiquitin ligase substrates. | 7 |
| 21513699 | 2011 | PRAJA1 is a ubiquitin ligase for the polycomb repressive complex 2 proteins. | 35 |
| 21461837 | 2011 | Protein microarrays for the identification of praja1 e3 ubiquitin ligase substrates. | 7 |
Citation
Dessen P
PJA1 (praja ring finger ubiquitin ligase 1)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/71935/pja1-(praja-ring-finger-ubiquitin-ligase-1)
