Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9033
MIM: 604532
HGNC: 9011
Ensembl: ENSG00000107593
Variants:
dbSNP: 9033
ClinVar: 9033
TCGA: ENSG00000107593
COSMIC: PKD2L1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000107593 | ENST00000318222 | Q9P0L9 |
| ENSG00000107593 | ENST00000465680 | H0YDN7 |
| ENSG00000107593 | ENST00000528248 | H0YET4 |
| ENSG00000107593 | ENST00000532547 | E9PRD1 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Taste transduction | KEGG | ko04742 |
| Taste transduction | KEGG | hsa04742 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36655284 | 2023 | Molecular Mechanism of L-Pyroglutamic Acid Interaction with the Human Sour Receptor. | 1 |
| 36922541 | 2023 | Polycystic kidney disease 2-like 1 channel contributes to the bitter aftertaste perception of quinine. | 0 |
| 37831088 | 2023 | Genetic Variants in WNT16 and PKD2L1 Locus Affect Heel Ultrasound Bone Stiffness: Analyses from the General Population and Patients Evaluated for Osteoporosis. | 1 |
| 36655284 | 2023 | Molecular Mechanism of L-Pyroglutamic Acid Interaction with the Human Sour Receptor. | 1 |
| 36922541 | 2023 | Polycystic kidney disease 2-like 1 channel contributes to the bitter aftertaste perception of quinine. | 0 |
| 37831088 | 2023 | Genetic Variants in WNT16 and PKD2L1 Locus Affect Heel Ultrasound Bone Stiffness: Analyses from the General Population and Patients Evaluated for Osteoporosis. | 1 |
| 33268808 | 2020 | Adaptive selection drives TRPP3 loss-of-function in an Ethiopian population. | 2 |
| 33268808 | 2020 | Adaptive selection drives TRPP3 loss-of-function in an Ethiopian population. | 2 |
| 31315976 | 2019 | Opening TRPP2 (PKD2L1) requires the transfer of gating charges. | 10 |
| 31315976 | 2019 | Opening TRPP2 (PKD2L1) requires the transfer of gating charges. | 10 |
| 29230552 | 2018 | Identification of clustered phosphorylation sites in PKD2L1: how PKD2L1 channel activation is regulated by cyclic adenosine monophosphate signaling pathway. | 6 |
| 29567962 | 2018 | Cryo-EM structure of the polycystic kidney disease-like channel PKD2L1. | 34 |
| 29899465 | 2018 | Hydrophobic pore gates regulate ion permeation in polycystic kidney disease 2 and 2L1 channels. | 38 |
| 30004384 | 2018 | Cryo-EM structure of the polycystin 2-l1 ion channel. | 27 |
| 29230552 | 2018 | Identification of clustered phosphorylation sites in PKD2L1: how PKD2L1 channel activation is regulated by cyclic adenosine monophosphate signaling pathway. | 6 |
Citation
Dessen P
PKD2L1 (polycystin 2 like 1, transient receptor potential cation channel)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/71940/pkd2l1-(polycystin-2-like-1-transient-receptor-potential-cation-channel)
