Identity
HGNC
LOCATION
1p36.32
LOCUSID
ALIAS
PLC-L4,PLC-eta2,PLCL4,PLCeta2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9651
MIM: 612836
HGNC: 29037
Ensembl: ENSG00000149527
Variants:
dbSNP: 9651
ClinVar: 9651
TCGA: ENSG00000149527
COSMIC: PLCH2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA26097 | CASR | Gene | Pathway | associated | |||
| PA33759 | PRKCA | Gene | Pathway | associated | |||
| PA33761 | PRKCB | Gene | Pathway | associated | |||
| PA33766 | PRKCG | Gene | Pathway | associated | |||
| PA33767 | PRKCH | Gene | Pathway | associated | |||
| PA33768 | PRKCI | Gene | Pathway | associated | |||
| PA33771 | PRKD1 | Gene | Pathway | associated | |||
| PA33775 | PRKCZ | Gene | Pathway | associated |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 21474938 | 2011 | Role of phosphoinositide-specific phospholipase C η2 in isolated and syndromic mental retardation. | 7 |
| 21474938 | 2011 | Role of phosphoinositide-specific phospholipase C η2 in isolated and syndromic mental retardation. | 7 |
| 20649401 | 2010 | Investigating SNPs flanking the D1S80 locus in a Tamil population from India. | 1 |
| 20649401 | 2010 | Investigating SNPs flanking the D1S80 locus in a Tamil population from India. | 1 |
| 18361507 | 2008 | Activation of human phospholipase C-eta2 by Gbetagamma. | 17 |
| 18361507 | 2008 | Activation of human phospholipase C-eta2 by Gbetagamma. | 17 |
| 15583837 | 2005 | Identification of a novel class of mammalian phosphoinositol-specific phospholipase C enzymes. | 14 |
| 15899900 | 2005 | A novel phospholipase C, PLC(eta)2, is a neuron-specific isozyme. | 36 |
| 16107206 | 2005 | Molecular cloning and characterization of PLC-eta2. | 27 |
| 15583837 | 2005 | Identification of a novel class of mammalian phosphoinositol-specific phospholipase C enzymes. | 14 |
| 15899900 | 2005 | A novel phospholipase C, PLC(eta)2, is a neuron-specific isozyme. | 36 |
| 16107206 | 2005 | Molecular cloning and characterization of PLC-eta2. | 27 |
Citation
Dessen P
PLCH2 (phospholipase C eta 2)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/71969/plch2-(phospholipase-c-eta-2)
