PLSCR4 (phospholipid scramblase 4)

2014-11-01  

Identity

HGNC
LOCATION
3q24
LOCUSID
ALIAS
TRA1
FUSION GENES

Other Information

Locus ID:

NCBI: 57088
MIM: 607612
HGNC: 16497
Ensembl: ENSG00000114698

Variants:

dbSNP: 57088
ClinVar: 57088
TCGA: ENSG00000114698
COSMIC: PLSCR4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000114698ENST00000354952Q9NRQ2
ENSG00000114698ENST00000383083E9PHR9
ENSG00000114698ENST00000433593Q9NRQ2
ENSG00000114698ENST00000446574Q9NRQ2
ENSG00000114698ENST00000460350C9J6E1
ENSG00000114698ENST00000460885C9JNW2
ENSG00000114698ENST00000476202C9J916
ENSG00000114698ENST00000481701C9J664
ENSG00000114698ENST00000493382Q9NRQ2
ENSG00000114698ENST00000498625C9J3P9

Expression (GTEx)

0
50
100
150

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
360771842022Phospholipid Scramblase 4 (PLSCR4) Regulates Adipocyte Differentiation via PIP3-Mediated AKT Activation.2
360771842022Phospholipid Scramblase 4 (PLSCR4) Regulates Adipocyte Differentiation via PIP3-Mediated AKT Activation.2
335770292021LINC00641 induces the malignant progression of colorectal carcinoma through the miRNA-424-5p/PLSCR4 feedback loop.3
347729942021Whole blood transcriptomic analysis reveals PLSCR4 as a potential marker for vaso-occlusive crises in sickle cell disease.2
335770292021LINC00641 induces the malignant progression of colorectal carcinoma through the miRNA-424-5p/PLSCR4 feedback loop.3
347729942021Whole blood transcriptomic analysis reveals PLSCR4 as a potential marker for vaso-occlusive crises in sickle cell disease.2
313225452019Long non-coding RNA LINC00641 suppresses non-small-cell lung cancer by sponging miR-424-5p to upregulate PLSCR4.25
314093842019DNA methylation signature is prognostic of choroid plexus tumor aggressiveness.19
313225452019Long non-coding RNA LINC00641 suppresses non-small-cell lung cancer by sponging miR-424-5p to upregulate PLSCR4.25
314093842019DNA methylation signature is prognostic of choroid plexus tumor aggressiveness.19
273636672016Snail represses the expression of human phospholipid scramblase 4 gene.0
273636672016Snail represses the expression of human phospholipid scramblase 4 gene.0
230896412012Biochemical and functional characterization of human phospholipid scramblase 4 (hPLSCR4).3
230896412012Biochemical and functional characterization of human phospholipid scramblase 4 (hPLSCR4).3
216900872011A minimal nuclear localization signal (NLS) in human phospholipid scramblase 4 that binds only the minor NLS-binding site of importin alpha1.34

Citation

Dessen P

PLSCR4 (phospholipid scramblase 4)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/72008/plscr4-(phospholipid-scramblase-4)