PMFBP1 (polyamine modulated factor 1 binding protein 1)

2014-11-01  

Identity

HGNC
LOCATION
16q22.2
LOCUSID
ALIAS
SPGF31,STAP
FUSION GENES

Other Information

Locus ID:

NCBI: 83449
MIM: 618085
HGNC: 17728
Ensembl: ENSG00000118557

Variants:

dbSNP: 83449
ClinVar: 83449
TCGA: ENSG00000118557
COSMIC: PMFBP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000118557ENST00000237353Q8TBY8
ENSG00000118557ENST00000355636Q8TBY8
ENSG00000118557ENST00000379073F8W771
ENSG00000118557ENST00000535461F5H4F8
ENSG00000118557ENST00000536211F5H0H9
ENSG00000118557ENST00000537392H0YFP6
ENSG00000118557ENST00000537465Q8TBY8
ENSG00000118557ENST00000537792F5H5J2
ENSG00000118557ENST00000539172F5GXW3
ENSG00000118557ENST00000540440F5GYR2

Expression (GTEx)

0
5
10
15
20
25
30

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
334843822021A novel homozygous missense mutation of PMFBP1 causes acephalic spermatozoa syndrome.7
340891952021Patients with acephalic spermatozoa syndrome linked to novel TSGA10/PMFBP1 variants have favorable pregnancy outcomes from intracytoplasmic sperm injection.2
334843822021A novel homozygous missense mutation of PMFBP1 causes acephalic spermatozoa syndrome.7
340891952021Patients with acephalic spermatozoa syndrome linked to novel TSGA10/PMFBP1 variants have favorable pregnancy outcomes from intracytoplasmic sperm injection.2
322854432020Novel mutations in PMFBP1, TSGA10 and SUN5: Expanding the spectrum of mutations that may cause acephalic spermatozoa.16
322854432020Novel mutations in PMFBP1, TSGA10 and SUN5: Expanding the spectrum of mutations that may cause acephalic spermatozoa.16
302986962019Biallelic mutations in PMFBP1 cause acephalic spermatozoa.24
302986962019Biallelic mutations in PMFBP1 cause acephalic spermatozoa.24

Citation

Dessen P

PMFBP1 (polyamine modulated factor 1 binding protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/72015/pmfbp1-(polyamine-modulated-factor-1-binding-protein-1)