PNLIPRP2 (pancreatic lipase related protein 2 (gene/pseudogene))

2014-11-01  

Identity

HGNC
PNLIPRP2
LOCATION
10q25.3
LOCUSID
5408
ALIAS
PLRP2

Other Information

Locus ID:

NCBI: 5408
MIM: 604423
HGNC: 9157
Ensembl: ENSG00000266200

Variants:

dbSNP: 5408
ClinVar: 5408
TCGA: ENSG00000266200
COSMIC: PNLIPRP2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000266200ENST00000591655P54317
ENSG00000266200ENST00000611850A0A087WX88

Expression (GTEx)

0
500
1000
1500
2000
2500
3000
3500
4000
4500
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Glycerolipid metabolismKEGGko00561
Glycerolipid metabolismKEGGhsa00561
Metabolic pathwaysKEGGhsa01100
Pancreatic secretionKEGGko04972
Pancreatic secretionKEGGhsa04972
Fat digestion and absorptionKEGGko04975
Fat digestion and absorptionKEGGhsa04975
Acylglycerol degradationKEGGhsa_M00098
Acylglycerol degradationKEGGM00098
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Lipid digestion, mobilization, and transportREACTOMER-HSA-73923
Digestion of dietary lipidREACTOMER-HSA-192456

References

Pubmed IDYearTitleCitations
380813812024Pancreatic lipase and its related proteins: where are we now?0
380813812024Pancreatic lipase and its related proteins: where are we now?0
304080632018The common truncation variant in pancreatic lipase related protein 2 (PNLIPRP2) is expressed poorly and does not alter risk for chronic pancreatitis.6
304080632018The common truncation variant in pancreatic lipase related protein 2 (PNLIPRP2) is expressed poorly and does not alter risk for chronic pancreatitis.6
276622542016Lysosomal Lipases PLRP2 and LPLA2 Process Mycobacterial Multi-acylated Lipids and Generate T Cell Stimulatory Antigens.18
276622542016Lysosomal Lipases PLRP2 and LPLA2 Process Mycobacterial Multi-acylated Lipids and Generate T Cell Stimulatory Antigens.18
264946242015The β5-Loop and Lid Domain Contribute to the Substrate Specificity of Pancreatic Lipase-related Protein 2 (PNLIPRP2).2
264946242015The β5-Loop and Lid Domain Contribute to the Substrate Specificity of Pancreatic Lipase-related Protein 2 (PNLIPRP2).2
237327752013Pancreatic lipase-related protein 2 digests fats in human milk and formula in concert with gastric lipase and carboxyl ester lipase.10
237327752013Pancreatic lipase-related protein 2 digests fats in human milk and formula in concert with gastric lipase and carboxyl ester lipase.10
215549822011Bis (monoacylglycero) phosphate interfacial properties and lipolysis by pancreatic lipase-related protein 2, an enzyme present in THP-1 human monocytes.7
216527022011Pancreatic lipase-related protein-2 (PLRP2) can contribute to dietary fat digestion in human newborns.18
218653482011BSSL and PLRP2: key enzymes for lipid digestion in the newborn examined using the Caco-2 cell line.15
215549822011Bis (monoacylglycero) phosphate interfacial properties and lipolysis by pancreatic lipase-related protein 2, an enzyme present in THP-1 human monocytes.7
216527022011Pancreatic lipase-related protein-2 (PLRP2) can contribute to dietary fat digestion in human newborns.18

Citation

Dessen P

PNLIPRP2 (pancreatic lipase related protein 2 (gene/pseudogene))

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/72023/pnliprp2-(pancreatic-lipase-related-protein-2-(gene-pseudogene))