PNO1 (partner of NOB1 homolog)

2014-11-01  

Identity

HGNC
PNO1
LOCATION
2p14
LOCUSID
56902
ALIAS
KHRBP1,RRP20
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 56902
MIM: 618710
HGNC: 32790
Ensembl: ENSG00000115946

Variants:

dbSNP: 56902
ClinVar: 56902
TCGA: ENSG00000115946
COSMIC: PNO1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000115946ENST00000263657Q9NRX1
ENSG00000115946ENST00000430742F8WBJ6

Expression (GTEx)

0
5
10
15
20
25
30
35
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
rRNA processingREACTOMER-HSA-72312
Major pathway of rRNA processing in the nucleolus and cytosolREACTOMER-HSA-6791226
rRNA processing in the nucleus and cytosolREACTOMER-HSA-8868773

References

Pubmed IDYearTitleCitations
366250872023Inhibition of ribosome assembly factor PNO1 by CRISPR/Cas9 technique suppresses lung adenocarcinoma and Notch pathway: Clinical application.2
379293512023Partner of NOB1 homolog transcriptionally activated by E2F transcription factor 1 promotes the malignant progression and inhibits ferroptosis of pancreatic cancer.1
380713812023PNO1 promotes the progression of osteosarcoma via TGF-β and YAP/TAZ pathway.0
366250872023Inhibition of ribosome assembly factor PNO1 by CRISPR/Cas9 technique suppresses lung adenocarcinoma and Notch pathway: Clinical application.2
379293512023Partner of NOB1 homolog transcriptionally activated by E2F transcription factor 1 promotes the malignant progression and inhibits ferroptosis of pancreatic cancer.1
380713812023PNO1 promotes the progression of osteosarcoma via TGF-β and YAP/TAZ pathway.0
354457332022Ribosome assembly factor PNO1 is associated with progression and promotes tumorigenesis in triple‑negative breast cancer.5
364467692022PNO1 inhibits autophagy-mediated ferroptosis by GSH metabolic reprogramming in hepatocellular carcinoma.18
354457332022Ribosome assembly factor PNO1 is associated with progression and promotes tumorigenesis in triple‑negative breast cancer.5
364467692022PNO1 inhibits autophagy-mediated ferroptosis by GSH metabolic reprogramming in hepatocellular carcinoma.18
337289672021PON1 polymorphisms can predict generalized anxiety and depressed mood in patients with multiple chemical sensitivity.4
338646612021Knockdown of PNO1 inhibits esophageal cancer progression.4
340501372021PNO1 regulates autophagy and apoptosis of hepatocellular carcinoma via the MAPK signaling pathway.22
337289672021PON1 polymorphisms can predict generalized anxiety and depressed mood in patients with multiple chemical sensitivity.4
338646612021Knockdown of PNO1 inhibits esophageal cancer progression.4

Citation

Dessen P

PNO1 (partner of NOB1 homolog)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/72029/pno1-(partner-of-nob1-homolog)