Identity
HGNC
LOCATION
Xq21.1
LOCUSID
ALIAS
BRAIN-4,BRN-4,BRN4,DFN3,DFNX2,OCT-9,OTF-9,OTF9
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5456
MIM: 300039
HGNC: 9217
Ensembl: ENSG00000196767
Variants:
dbSNP: 5456
ClinVar: 5456
TCGA: ENSG00000196767
COSMIC: POU3F4
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000196767 | ENST00000644024 | A0A2R8Y739 |
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37929330 | 2024 | Genome sequencing detects a balanced pericentric inversion with breakpoints that impact the DMD and upstream region of POU3F4 genes. | 1 |
| 37929330 | 2024 | Genome sequencing detects a balanced pericentric inversion with breakpoints that impact the DMD and upstream region of POU3F4 genes. | 1 |
| 34133399 | 2022 | X-linked Malformation Deafness: Neurodevelopmental Symptoms Are Common in Children With IP3 Malformation and Mutation in POU3F4. | 7 |
| 35367201 | 2022 | REST Inactivation and Coexpression of ASCL1 and POU3F4 Are Necessary for the Complete Transformation of RB1/TP53-Inactivated Lung Adenocarcinoma into Neuroendocrine Carcinoma. | 3 |
| 34133399 | 2022 | X-linked Malformation Deafness: Neurodevelopmental Symptoms Are Common in Children With IP3 Malformation and Mutation in POU3F4. | 7 |
| 35367201 | 2022 | REST Inactivation and Coexpression of ASCL1 and POU3F4 Are Necessary for the Complete Transformation of RB1/TP53-Inactivated Lung Adenocarcinoma into Neuroendocrine Carcinoma. | 3 |
| 33398372 | 2021 | Research progress of the transcription factor Brn4 (Review). | 3 |
| 33860785 | 2021 | Study of complex structural variations of X-linked deafness-2 based on single-molecule sequencing. | 3 |
| 33976695 | 2021 | Next-Generation Sequencing Identifies Pathogenic Variants in HGF, POU3F4, TECTA, and MYO7A in Consanguineous Pakistani Deaf Families. | 2 |
| 33398372 | 2021 | Research progress of the transcription factor Brn4 (Review). | 3 |
| 33860785 | 2021 | Study of complex structural variations of X-linked deafness-2 based on single-molecule sequencing. | 3 |
| 33976695 | 2021 | Next-Generation Sequencing Identifies Pathogenic Variants in HGF, POU3F4, TECTA, and MYO7A in Consanguineous Pakistani Deaf Families. | 2 |
| 31786483 | 2020 | Genetic identification and molecular modeling characterization of a novel POU3F4 variant in two Italian deaf brothers. | 7 |
| 31786483 | 2020 | Genetic identification and molecular modeling characterization of a novel POU3F4 variant in two Italian deaf brothers. | 7 |
| 31371344 | 2019 | BRN4 Is a Novel Driver of Neuroendocrine Differentiation in Castration-Resistant Prostate Cancer and Is Selectively Released in Extracellular Vesicles with BRN2. | 37 |
Citation
Dessen P
POU3F4 (POU class 3 homeobox 4)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/72094/pou3f4-(pou-class-3-homeobox-4)
