Identity
HGNC
LOCATION
6p21.33
LOCUSID
ALIAS
HKMT1098,KIAA1949
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 170954
MIM: 610990
HGNC: 29413
Ensembl: ENSG00000146112
Variants:
dbSNP: 170954
ClinVar: 170954
TCGA: ENSG00000146112
COSMIC: PPP1R18
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA443622 | Carcinoma, Non-Small-Cell Lung | Disease | ClinicalAnnotation | associated | PD | 31616045 | |
| PA445846 | Thrombocytopenia | Disease | ClinicalAnnotation | associated | PD | 31616045 | |
| PA448803 | carboplatin | Chemical | ClinicalAnnotation | associated | PD | 31616045 | |
| PA449748 | gemcitabine | Chemical | ClinicalAnnotation | associated | PD | 31616045 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 32800345 | 2020 | Identification of phostensin in association with Eps 15 homology domain-containing protein 1 (EHD1) and EHD4. | 0 |
| 32800345 | 2020 | Identification of phostensin in association with Eps 15 homology domain-containing protein 1 (EHD1) and EHD4. | 0 |
| 29158294 | 2018 | The Actin-Binding Protein PPP1r18 Regulates Maturation, Actin Organization, and Bone Resorption Activity of Osteoclasts. | 10 |
| 29158294 | 2018 | The Actin-Binding Protein PPP1r18 Regulates Maturation, Actin Organization, and Bone Resorption Activity of Osteoclasts. | 10 |
| 21804078 | 2011 | Immunolocalization of phostensin in lymphatic cells and tissues. | 6 |
| 21804078 | 2011 | Immunolocalization of phostensin in lymphatic cells and tissues. | 6 |
| 19622346 | 2009 | Phostensin caps to the pointed end of actin filaments and modulates actin dynamics. | 16 |
| 19851445 | 2009 | High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. | 58 |
| 19622346 | 2009 | Phostensin caps to the pointed end of actin filaments and modulates actin dynamics. | 16 |
| 19851445 | 2009 | High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. | 58 |
| 17374523 | 2007 | Identification of phostensin, a PP1 F-actin cytoskeleton targeting subunit. | 20 |
| 17374523 | 2007 | Identification of phostensin, a PP1 F-actin cytoskeleton targeting subunit. | 20 |
Citation
Dessen P
PPP1R18 (protein phosphatase 1 regulatory subunit 18)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/72143/ppp1r18-(protein-phosphatase-1-regulatory-subunit-18)
