PRDM15 (PR/SET domain 15)

2014-11-01  

Identity

HGNC
PRDM15
LOCATION
21q22.3
LOCUSID
63977
ALIAS
C21orf83,PFM15,ZNF298

Other Information

Locus ID:

NCBI: 63977
MIM: 617692
HGNC: 13999
Ensembl: ENSG00000141956

Variants:

dbSNP: 63977
ClinVar: 63977
TCGA: ENSG00000141956
COSMIC: PRDM15

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000141956ENST00000269844P57071
ENSG00000141956ENST00000398548P57071
ENSG00000141956ENST00000422911P57071
ENSG00000141956ENST00000433067P57071
ENSG00000141956ENST00000441787Q4W8S1
ENSG00000141956ENST00000447016E7ER26
ENSG00000141956ENST00000447207E7ER26
ENSG00000141956ENST00000449395P57071

Expression (GTEx)

0
5
10
15
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
366748422023Proof-of-Concept Method to Study Uncharacterized Methyltransferases Using PRDM15.0
378172272023The RNA methyltransferase METTL16 enhances cholangiocarcinoma growth through PRDM15-mediated FGFR4 expression.3
366748422023Proof-of-Concept Method to Study Uncharacterized Methyltransferases Using PRDM15.0
378172272023The RNA methyltransferase METTL16 enhances cholangiocarcinoma growth through PRDM15-mediated FGFR4 expression.3
335938232021Mutations in PRDM15 Are a Novel Cause of Galloway-Mowat Syndrome.11
335938232021Mutations in PRDM15 Are a Novel Cause of Galloway-Mowat Syndrome.11
319500802020PRDM15 loss of function links NOTCH and WNT/PCP signaling to patterning defects in holoprosencephaly.10
322227102020PRDM15 Is Associated with Risk of Chronic Obstructive Pulmonary Disease in a Rural Population in Chile.4
319500802020PRDM15 loss of function links NOTCH and WNT/PCP signaling to patterning defects in holoprosencephaly.10
322227102020PRDM15 Is Associated with Risk of Chronic Obstructive Pulmonary Disease in a Rural Population in Chile.4
287402642017PRDM15 safeguards naive pluripotency by transcriptionally regulating WNT and MAPK-ERK signaling.29
287402642017PRDM15 safeguards naive pluripotency by transcriptionally regulating WNT and MAPK-ERK signaling.29

Citation

Dessen P

PRDM15 (PR/SET domain 15)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/72195/prdm15-(pr-set-domain-15)