PRICKLE3 (prickle planar cell polarity protein 3)

2014-11-01  

Identity

HGNC
PRICKLE3
LOCATION
Xp11.23
LOCUSID
4007
ALIAS
LMO6,LOAM,Pk3
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 4007
MIM: 300111
HGNC: 6645
Ensembl: ENSG00000012211

Variants:

dbSNP: 4007
ClinVar: 4007
TCGA: ENSG00000012211
COSMIC: PRICKLE3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000012211ENST00000376317A0A0A0MRT7
ENSG00000012211ENST00000432913H7BZP7
ENSG00000012211ENST00000453382H0Y413
ENSG00000012211ENST00000540849F5H4N2
ENSG00000012211ENST00000599218O43900
ENSG00000012211ENST00000599218A0A024QYW5

Expression (GTEx)

0
5
10
15
20
25
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
325161352020PRICKLE3 linked to ATPase biogenesis manifested Leber's hereditary optic neuropathy.31
325161352020PRICKLE3 linked to ATPase biogenesis manifested Leber's hereditary optic neuropathy.31

Citation

Dessen P

PRICKLE3 (prickle planar cell polarity protein 3)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/72206/gene-explorer/