PRSS56 (serine protease 56)

2014-11-01  

Identity

HGNC
LOCATION
2q37.1
LOCUSID
ALIAS
MCOP6

Other Information

Locus ID:

NCBI: 646960
MIM: 613858
HGNC: 39433
Ensembl: ENSG00000237412

Variants:

dbSNP: 646960
ClinVar: 646960
TCGA: ENSG00000237412
COSMIC: PRSS56

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000237412ENST00000617714P0CW18

Expression (GTEx)

0
1
2
3
4
5
6

References

Pubmed IDYearTitleCitations
375015622023Pathogenic variants of MFRP and PRSS56 genes are major causes of nanophthalmos in Japanese patients.0
375015622023Pathogenic variants of MFRP and PRSS56 genes are major causes of nanophthalmos in Japanese patients.0
319927372020The majority of autosomal recessive nanophthalmos and posterior microphthalmia can be attributed to biallelic sequence and structural variants in MFRP and PRSS56.12
320524052020The genetic and clinical landscape of nanophthalmos and posterior microphthalmos in an Australian cohort.10
321184952020Novel mutations in MFRP and PRSS56 are associated with posterior microphthalmos.6
321520632020Loss of PRSS56 function leads to ocular angle defects and increased susceptibility to high intraocular pressure.9
332039482020Novel TMEM98, MFRP, PRSS56 variants in a large United States high hyperopia and nanophthalmos cohort.8
319927372020The majority of autosomal recessive nanophthalmos and posterior microphthalmia can be attributed to biallelic sequence and structural variants in MFRP and PRSS56.12
320524052020The genetic and clinical landscape of nanophthalmos and posterior microphthalmos in an Australian cohort.10
321184952020Novel mutations in MFRP and PRSS56 are associated with posterior microphthalmos.6
321520632020Loss of PRSS56 function leads to ocular angle defects and increased susceptibility to high intraocular pressure.9
332039482020Novel TMEM98, MFRP, PRSS56 variants in a large United States high hyperopia and nanophthalmos cohort.8
312660622019Detection of Clinically Relevant Genetic Variants in Chinese Patients With Nanophthalmos by Trio-Based Whole-Genome Sequencing Study.15
312660622019Detection of Clinically Relevant Genetic Variants in Chinese Patients With Nanophthalmos by Trio-Based Whole-Genome Sequencing Study.15
231277492013Biometric and molecular characterization of clinically diagnosed posterior microphthalmos.20

Citation

Dessen P

PRSS56 (serine protease 56)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/72318/prss56-(serine-protease-56)