PRSS57 (serine protease 57)

2014-11-01  

Identity

HGNC
LOCATION
19p13.3
LOCUSID
ALIAS
NSP4,PRSSL1,UNQ782

Other Information

Locus ID:

NCBI: 400668
HGNC: 31397
Ensembl: ENSG00000185198

Variants:

dbSNP: 400668
ClinVar: 400668
TCGA: ENSG00000185198
COSMIC: PRSS57

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000185198ENST00000329267A0A0A0MR61
ENSG00000185198ENST00000613411Q6UWY2

Expression (GTEx)

0
1
2
3
4

References

Pubmed IDYearTitleCitations
374023732023The NSP4 T492I mutation increases SARS-CoV-2 infectivity by altering non-structural protein cleavage.5
374023732023The NSP4 T492I mutation increases SARS-CoV-2 infectivity by altering non-structural protein cleavage.5
251564282014Structures of neutrophil serine protease 4 reveal an unusual mechanism of substrate recognition by a trypsin-fold protease.12
251564282014Structures of neutrophil serine protease 4 reveal an unusual mechanism of substrate recognition by a trypsin-fold protease.12
239041612013NSP4 is stored in azurophil granules and released by activated neutrophils as active endoprotease with restricted specificity.32
239041612013NSP4 is stored in azurophil granules and released by activated neutrophils as active endoprotease with restricted specificity.32

Citation

Dessen P

PRSS57 (serine protease 57)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/72319/prss57-(serine-protease-57)