Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 170679
MIM: 613525
HGNC: 17202
Ensembl: ENSG00000204540
Variants:
dbSNP: 170679
ClinVar: 170679
TCGA: ENSG00000204540
COSMIC: PSORS1C1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000204540 | ENST00000259881 | Q9UIG5 |
| ENSG00000204540 | ENST00000259881 | D2IYL0 |
| ENSG00000204540 | ENST00000481450 | Q2M3K9 |
| ENSG00000204540 | ENST00000547221 | A0A0C4DGJ2 |
Expression (GTEx)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA166120927 | drug reaction with eosinophilia and systemic symptoms | Disease | ClinicalAnnotation, VariantAnnotation | associated | PD | ||
| PA166120929 | severe cutaneous adverse reactions | Disease | ClinicalAnnotation | associated | PD | 21801394, 29193002 | |
| PA443434 | Arthritis, Rheumatoid | Disease | ClinicalAnnotation | associated | PD | ||
| PA443622 | Carcinoma, Non-Small-Cell Lung | Disease | ClinicalAnnotation | associated | PD | 31616045 | |
| PA444059 | Epidermal Necrolysis, Toxic | Disease | ClinicalAnnotation | associated | PD | 21801394, 29193002 | |
| PA445738 | Stevens-Johnson Syndrome | Disease | ClinicalAnnotation, VariantAnnotation | associated | PD | 21801394, 29193002 | |
| PA445846 | Thrombocytopenia | Disease | ClinicalAnnotation | associated | PD | 31616045 | |
| PA448320 | allopurinol | Chemical | ClinicalAnnotation, VariantAnnotation | associated | PD | 21801394, 29193002 | |
| PA448803 | carboplatin | Chemical | ClinicalAnnotation | associated | PD | 31616045 | |
| PA449515 | etanercept | Chemical | ClinicalAnnotation | associated | PD | ||
| PA449748 | gemcitabine | Chemical | ClinicalAnnotation | associated | PD | 31616045 | |
| PA450616 | nevirapine | Chemical | Literature | not associated | 24322967 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34325607 | 2022 | Psoriasis Susceptibility 1 Candidate 1 (PSORS1C1) Polymorphism is Associated with Autoimmune Thyroid Disease in a Chinese Han Population. | 2 |
| 34325607 | 2022 | Psoriasis Susceptibility 1 Candidate 1 (PSORS1C1) Polymorphism is Associated with Autoimmune Thyroid Disease in a Chinese Han Population. | 2 |
| 29193002 | 2018 | The minor alleles HCP5 rs3099844 A and PSORS1C1 rs3131003 G are associated with allopurinol-induced severe cutaneous adverse reactions in Han Chinese: a multicentre retrospective case-control clinical study. | 5 |
| 29589160 | 2018 | HLA-C*06:02-independent, gender-related association of PSORS1C3 and PSORS1C1/CDSN single-nucleotide polymorphisms with risk and severity of psoriasis. | 17 |
| 29193002 | 2018 | The minor alleles HCP5 rs3099844 A and PSORS1C1 rs3131003 G are associated with allopurinol-induced severe cutaneous adverse reactions in Han Chinese: a multicentre retrospective case-control clinical study. | 5 |
| 29589160 | 2018 | HLA-C*06:02-independent, gender-related association of PSORS1C3 and PSORS1C1/CDSN single-nucleotide polymorphisms with risk and severity of psoriasis. | 17 |
| 28107378 | 2017 | Polymorphisms in STAT4, PTPN2, PSORS1C1 and TRAF3IP2 Genes Are Associated with the Response to TNF Inhibitors in Patients with Rheumatoid Arthritis. | 11 |
| 28107378 | 2017 | Polymorphisms in STAT4, PTPN2, PSORS1C1 and TRAF3IP2 Genes Are Associated with the Response to TNF Inhibitors in Patients with Rheumatoid Arthritis. | 11 |
| 27342690 | 2016 | Polymorphisms in STAT-4, IL-10, PSORS1C1, PTPN2 and MIR146A genes are associated differently with prognostic factors in Italian patients affected by rheumatoid arthritis. | 18 |
| 27342690 | 2016 | Polymorphisms in STAT-4, IL-10, PSORS1C1, PTPN2 and MIR146A genes are associated differently with prognostic factors in Italian patients affected by rheumatoid arthritis. | 18 |
| 24210685 | 2014 | PSORS1C1/CDSN is associated with ankylosing spondylitis. | 2 |
| 24406073 | 2014 | Genome-wide association study and admixture mapping identify different asthma-associated loci in Latinos: the Genes-environments & Admixture in Latino Americans study. | 66 |
| 24210685 | 2014 | PSORS1C1/CDSN is associated with ankylosing spondylitis. | 2 |
| 24406073 | 2014 | Genome-wide association study and admixture mapping identify different asthma-associated loci in Latinos: the Genes-environments & Admixture in Latino Americans study. | 66 |
| 22896740 | 2013 | Confirmation of TNIP1 but not RHOB and PSORS1C1 as systemic sclerosis risk factors in a large independent replication study. | 24 |
Citation
Dessen P
PSORS1C1 (psoriasis susceptibility 1 candidate 1)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/72359/psors1c1-(psoriasis-susceptibility-1-candidate-1)
