PSORS1C2 (psoriasis susceptibility 1 candidate 2)

2014-11-01  

Identity

HGNC
LOCATION
6p21.33
LOCUSID
ALIAS
C6orf17,SPR1

Other Information

Locus ID:

NCBI: 170680
MIM: 613526
HGNC: 17199
Ensembl: ENSG00000204538

Variants:

dbSNP: 170680
ClinVar: 170680
TCGA: ENSG00000204538
COSMIC: PSORS1C2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000204538ENST00000259845Q9UIG4
ENSG00000204538ENST00000259845A0A1U9X9A6

Expression (GTEx)

0
50
100
150
200

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
279434522017Phylogenetic profiling and gene expression studies implicate a primary role of PSORS1C2 in terminal differentiation of keratinocytes.10
279434522017Phylogenetic profiling and gene expression studies implicate a primary role of PSORS1C2 in terminal differentiation of keratinocytes.10
228213322013The HLA-Cw*06 allele and -1149 G/T polymorphism of extrapituitary promoter of PRL gene as a possible common genetic predisposing factors to psoriasis vulgaris and psoriatic arthritis in Czech population.3
228213322013The HLA-Cw*06 allele and -1149 G/T polymorphism of extrapituitary promoter of PRL gene as a possible common genetic predisposing factors to psoriasis vulgaris and psoriatic arthritis in Czech population.3
198514452009High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions.58
198514452009High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions.58
155231602004Correlation of HLA-Cw*06 allele frequency with some clinical features of psoriasis vulgaris in the population of northern Poland.7
155231602004Correlation of HLA-Cw*06 allele frequency with some clinical features of psoriasis vulgaris in the population of northern Poland.7
128234452003SPR1 gene near HLA-C is unlikely to be a psoriasis susceptibility gene.4
129303002003Polymorphisms in the SEEK1 and SPR1 genes on 6p21.3 associate with psoriasis in the Swedish population.16
128234452003SPR1 gene near HLA-C is unlikely to be a psoriasis susceptibility gene.4
129303002003Polymorphisms in the SEEK1 and SPR1 genes on 6p21.3 associate with psoriasis in the Swedish population.16

Citation

Dessen P

PSORS1C2 (psoriasis susceptibility 1 candidate 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/72360/psors1c2-(psoriasis-susceptibility-1-candidate-2)