PYGO1 (pygopus family PHD finger 1)

2014-11-01  

Identity

HGNC
LOCATION
15q21.3
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 26108
MIM: 606902
HGNC: 30256
Ensembl: ENSG00000171016

Variants:

dbSNP: 26108
ClinVar: 26108
TCGA: ENSG00000171016
COSMIC: PYGO1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000171016ENST00000302000Q9Y3Y4
ENSG00000171016ENST00000563719Q9Y3Y4
ENSG00000171016ENST00000645724Q9Y3Y4

Expression (GTEx)

0
1
2
3
4
5
6
7
8
9
10

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by WntREACTOMER-HSA-195721
TCF dependent signaling in response to WNTREACTOMER-HSA-201681
Formation of the beta-catenin:TCF transactivating complexREACTOMER-HSA-201722
Deactivation of the beta-catenin transactivating complexREACTOMER-HSA-3769402

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
363980312022Pygo1 Regulates the Behavior of Human Non-Small-Cell Lung Cancer via the Wnt/β-Catenin Pathway.2
363980312022Pygo1 Regulates the Behavior of Human Non-Small-Cell Lung Cancer via the Wnt/β-Catenin Pathway.2
204039152010Single nucleotide polymorphisms in Wnt signaling and cell death pathway genes and susceptibility to colorectal cancer.13
204039152010Single nucleotide polymorphisms in Wnt signaling and cell death pathway genes and susceptibility to colorectal cancer.13
184987522008Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex.99
184987522008Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex.99

Citation

Dessen P

PYGO1 (pygopus family PHD finger 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/72431/pygo1-(pygopus-family-phd-finger-1)