Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23475
MIM: 606248
HGNC: 9755
Ensembl: ENSG00000103485
Variants:
dbSNP: 23475
ClinVar: 23475
TCGA: ENSG00000103485
COSMIC: QPRT
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000103485 | ENST00000395384 | Q15274 |
| ENSG00000103485 | ENST00000449759 | Q15274 |
| ENSG00000103485 | ENST00000449759 | C9JCJ5 |
| ENSG00000103485 | ENST00000562473 | H3BP73 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37723185 | 2023 | A comprehensive analysis of the role of QPRT in breast cancer. | 2 |
| 37723185 | 2023 | A comprehensive analysis of the role of QPRT in breast cancer. | 2 |
| 32238439 | 2020 | Targeting NAD(+) Biosynthesis Overcomes Panobinostat and Bortezomib-Induced Malignant Glioma Resistance. | 8 |
| 32716908 | 2020 | Silencing DSCAM-AS1 suppresses the growth and invasion of ER-positive breast cancer cells by downregulating both DCTPP1 and QPRT. | 13 |
| 32238439 | 2020 | Targeting NAD(+) Biosynthesis Overcomes Panobinostat and Bortezomib-Induced Malignant Glioma Resistance. | 8 |
| 32716908 | 2020 | Silencing DSCAM-AS1 suppresses the growth and invasion of ER-positive breast cancer cells by downregulating both DCTPP1 and QPRT. | 13 |
| 30443311 | 2018 | Loss of the Chr16p11.2 ASD candidate gene QPRT leads to aberrant neuronal differentiation in the SH-SY5Y neuronal cell model. | 24 |
| 30443311 | 2018 | Loss of the Chr16p11.2 ASD candidate gene QPRT leads to aberrant neuronal differentiation in the SH-SY5Y neuronal cell model. | 24 |
| 27889611 | 2017 | Anti-apoptotic quinolinate phosphoribosyltransferase (QPRT) is a target gene of Wilms' tumor gene 1 (WT1) protein in leukemic cells. | 19 |
| 28724915 | 2017 | Quinolinate Phosphoribosyltransferase is an Antiviral Host Factor Against Hepatitis C Virus Infection. | 9 |
| 27889611 | 2017 | Anti-apoptotic quinolinate phosphoribosyltransferase (QPRT) is a target gene of Wilms' tumor gene 1 (WT1) protein in leukemic cells. | 19 |
| 28724915 | 2017 | Quinolinate Phosphoribosyltransferase is an Antiviral Host Factor Against Hepatitis C Virus Infection. | 9 |
| 26805589 | 2016 | Structural Insights into the Quaternary Catalytic Mechanism of Hexameric Human Quinolinate Phosphoribosyltransferase, a Key Enzyme in de novo NAD Biosynthesis. | 14 |
| 26805589 | 2016 | Structural Insights into the Quaternary Catalytic Mechanism of Hexameric Human Quinolinate Phosphoribosyltransferase, a Key Enzyme in de novo NAD Biosynthesis. | 14 |
| 24038671 | 2014 | The crystal structure of human quinolinic acid phosphoribosyltransferase in complex with its inhibitor phthalic acid. | 12 |
Citation
Dessen P
QPRT (quinolinate phosphoribosyltransferase)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/72441/tumors-explorer/gene-explorer/
