Identity
HGNC
LOCATION
19p13.2
LOCUSID
ALIAS
FP3235,TGT,TGUT
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 81890
MIM: 609615
HGNC: 23797
Ensembl: ENSG00000213339
Variants:
dbSNP: 81890
ClinVar: 81890
TCGA: ENSG00000213339
COSMIC: QTRT1
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Gene Expression | REACTOME | R-HSA-74160 |
| tRNA processing | REACTOME | R-HSA-72306 |
| tRNA modification in the nucleus and cytosol | REACTOME | R-HSA-6782315 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38181786 | 2024 | Structural and functional insights into tRNA recognition by human tRNA guanine transglycosylase. | 0 |
| 38181786 | 2024 | Structural and functional insights into tRNA recognition by human tRNA guanine transglycosylase. | 0 |
| 34009357 | 2021 | The human tRNA-guanine transglycosylase displays promiscuous nucleobase preference but strict tRNA specificity. | 4 |
| 34009357 | 2021 | The human tRNA-guanine transglycosylase displays promiscuous nucleobase preference but strict tRNA specificity. | 4 |
| 23704982 | 2013 | Investigation of specificity determinants in bacterial tRNA-guanine transglycosylase reveals queuine, the substrate of its eucaryotic counterpart, as inhibitor. | 8 |
| 23704982 | 2013 | Investigation of specificity determinants in bacterial tRNA-guanine transglycosylase reveals queuine, the substrate of its eucaryotic counterpart, as inhibitor. | 8 |
| 21131277 | 2011 | Evolution of eukaryal tRNA-guanine transglycosylase: insight gained from the heterocyclic substrate recognition by the wild-type and mutant human and Escherichia coli tRNA-guanine transglycosylases. | 12 |
| 21640076 | 2011 | Differential heterocyclic substrate recognition by, and pteridine inhibition of E. coli and human tRNA-guanine transglycosylases. | 3 |
| 21131277 | 2011 | Evolution of eukaryal tRNA-guanine transglycosylase: insight gained from the heterocyclic substrate recognition by the wild-type and mutant human and Escherichia coli tRNA-guanine transglycosylases. | 12 |
| 21640076 | 2011 | Differential heterocyclic substrate recognition by, and pteridine inhibition of E. coli and human tRNA-guanine transglycosylases. | 3 |
| 20354154 | 2010 | Characterization of the human tRNA-guanine transglycosylase: confirmation of the heterodimeric subunit structure. | 36 |
| 20354154 | 2010 | Characterization of the human tRNA-guanine transglycosylase: confirmation of the heterodimeric subunit structure. | 36 |
Citation
Dessen P
QTRT1 (queuine tRNA-ribosyltransferase catalytic subunit 1)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/72445/qtrt1-(queuine-trna-ribosyltransferase-catalytic-subunit-1)
