RBM25 (RNA binding motif protein 25)

2014-11-01  

Identity

HGNC
RBM25
LOCATION
14q24.2
LOCUSID
58517
ALIAS
NET52,RED120,RNPC7,S164,Snu71,fSAP94
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 58517
MIM: 612427
HGNC: 23244
Ensembl: ENSG00000119707

Variants:

dbSNP: 58517
ClinVar: 58517
TCGA: ENSG00000119707
COSMIC: RBM25

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000119707ENST00000261973P49756
ENSG00000119707ENST00000525161E9PSE8
ENSG00000119707ENST00000525321P49756
ENSG00000119707ENST00000526754P49756
ENSG00000119707ENST00000527432P49756
ENSG00000119707ENST00000528081P49756
ENSG00000119707ENST00000531500E9PQU5
ENSG00000119707ENST00000532192H0YE46

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
SpliceosomeKEGGko03040
SpliceosomeKEGGhsa03040

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
378118812023Alternative splicing of BCL-x is controlled by RBM25 binding to a G-quadruplex in BCL-x pre-mRNA.2
378118812023Alternative splicing of BCL-x is controlled by RBM25 binding to a G-quadruplex in BCL-x pre-mRNA.2
348094442022Posttranscriptional Regulation of the Human LDL Receptor by the U2-Spliceosome.5
348094442022Posttranscriptional Regulation of the Human LDL Receptor by the U2-Spliceosome.5
338308652021Prognostic alternative splicing regulatory network of RBM25 in hepatocellular carcinoma.3
338308652021Prognostic alternative splicing regulatory network of RBM25 in hepatocellular carcinoma.3
305318342019Dysregulation of p53-RBM25-mediated circAMOTL1L biogenesis contributes to prostate cancer progression through the circAMOTL1L-miR-193a-5p-Pcdha pathway.90
306355672019The splicing factor RBM25 controls MYC activity in acute myeloid leukemia.31
315869882019Systematic profiling of alternative splicing events and splicing factors in left- and right-sided colon cancer.18
305318342019Dysregulation of p53-RBM25-mediated circAMOTL1L biogenesis contributes to prostate cancer progression through the circAMOTL1L-miR-193a-5p-Pcdha pathway.90
306355672019The splicing factor RBM25 controls MYC activity in acute myeloid leukemia.31
315869882019Systematic profiling of alternative splicing events and splicing factors in left- and right-sided colon cancer.18
286557592017RBM25 is a global splicing factor promoting inclusion of alternatively spliced exons and is itself regulated by lysine mono-methylation.24
286557592017RBM25 is a global splicing factor promoting inclusion of alternatively spliced exons and is itself regulated by lysine mono-methylation.24
231902622013Crystal structure and functional characterization of the human RBM25 PWI domain and its flanking basic region.7

Citation

Dessen P

RBM25 (RNA binding motif protein 25)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/72518/rbm25-(rna-binding-motif-protein-25)