RDH8 (retinol dehydrogenase 8)

2014-11-01  

Identity

HGNC
LOCATION
19p13.2
LOCUSID
ALIAS
PRRDH,SDR28C2
FUSION GENES

Other Information

Locus ID:

NCBI: 50700
MIM: 608575
HGNC: 14423
Ensembl: ENSG00000080511

Variants:

dbSNP: 50700
ClinVar: 50700
TCGA: ENSG00000080511
COSMIC: RDH8

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000080511ENST00000587782K7EKT5
ENSG00000080511ENST00000591589Q9NYR8
ENSG00000080511ENST00000591589K7ELF7
ENSG00000080511ENST00000651512K7ELF7

Expression (GTEx)

0
1
2
3
4
5

Pathways

PathwaySourceExternal ID
Retinol metabolismKEGGko00830
Retinol metabolismKEGGhsa00830
Metabolic pathwaysKEGGhsa01100
Signal TransductionREACTOMER-HSA-162582
Visual phototransductionREACTOMER-HSA-2187338
The canonical retinoid cycle in rods (twilight vision)REACTOMER-HSA-2453902

References

Pubmed IDYearTitleCitations
376287102023A Splicing Variant in RDH8 Is Associated with Autosomal Recessive Stargardt Macular Dystrophy.1
376287102023A Splicing Variant in RDH8 Is Associated with Autosomal Recessive Stargardt Macular Dystrophy.1
342977692021Targeted capture sequencing identifies genetic variations of GRK4 and RDH8 in Han Chinese with essential hypertension in Xinjiang.2
342977692021Targeted capture sequencing identifies genetic variations of GRK4 and RDH8 in Han Chinese with essential hypertension in Xinjiang.2
222207222012Retinal cone and rod photoreceptor cells exhibit differential susceptibility to light-induced damage.21
222207222012Retinal cone and rod photoreceptor cells exhibit differential susceptibility to light-induced damage.21
210430512010Investigation of the association between all-trans-retinol dehydrogenase (RDH8) polymorphisms and high myopia in Chinese.3
210430512010Investigation of the association between all-trans-retinol dehydrogenase (RDH8) polymorphisms and high myopia in Chinese.3
210430512010Investigation of the association between all-trans-retinol dehydrogenase (RDH8) polymorphisms and high myopia in Chinese.3
210430512010Investigation of the association between all-trans-retinol dehydrogenase (RDH8) polymorphisms and high myopia in Chinese.3
157557272005Role of photoreceptor-specific retinol dehydrogenase in the retinoid cycle in vivo.107
157557272005Role of photoreceptor-specific retinol dehydrogenase in the retinoid cycle in vivo.107

Citation

Dessen P

RDH8 (retinol dehydrogenase 8)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/72566/rdh8-(retinol-dehydrogenase-8)