Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 54933
MIM: 608962
HGNC: 16083
Ensembl: ENSG00000158315
Variants:
dbSNP: 54933
ClinVar: 54933
TCGA: ENSG00000158315
COSMIC: RHBDL2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000158315 | ENST00000289248 | Q9NX52 |
| ENSG00000158315 | ENST00000372990 | Q9NX52 |
| ENSG00000158315 | ENST00000540558 | Q9NX52 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33566379 | 2021 | Interleukin-11 (IL-11) receptor cleavage by the rhomboid protease RHBDL2 induces IL-11 trans-signaling. | 11 |
| 33566379 | 2021 | Interleukin-11 (IL-11) receptor cleavage by the rhomboid protease RHBDL2 induces IL-11 trans-signaling. | 11 |
| 21494248 | 2011 | Mammalian EGF receptor activation by the rhomboid protease RHBDL2. | 45 |
| 21833011 | 2011 | Functions of rhomboid family protease RHBDL2 and thrombomodulin in wound healing. | 21 |
| 21494248 | 2011 | Mammalian EGF receptor activation by the rhomboid protease RHBDL2. | 45 |
| 21833011 | 2011 | Functions of rhomboid family protease RHBDL2 and thrombomodulin in wound healing. | 21 |
| 20080650 | 2010 | Inherited genetic variant predisposes to aggressive but not indolent prostate cancer. | 57 |
| 20080650 | 2010 | Inherited genetic variant predisposes to aggressive but not indolent prostate cancer. | 57 |
| 19850051 | 2009 | The processing of human rhomboid intramembrane serine protease RHBDL2 is required for its proteolytic activity. | 3 |
| 19850051 | 2009 | The processing of human rhomboid intramembrane serine protease RHBDL2 is required for its proteolytic activity. | 3 |
| 15047175 | 2004 | Intramembrane cleavage of ephrinB3 by the human rhomboid family protease, RHBDL2. | 29 |
| 15047175 | 2004 | Intramembrane cleavage of ephrinB3 by the human rhomboid family protease, RHBDL2. | 29 |
| 12820957 | 2003 | Substrate specificity of rhomboid intramembrane proteases is governed by helix-breaking residues in the substrate transmembrane domain. | 93 |
| 12820957 | 2003 | Substrate specificity of rhomboid intramembrane proteases is governed by helix-breaking residues in the substrate transmembrane domain. | 93 |
Citation
Dessen P
RHBDL2 (rhomboid like 2)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/72625/meetings/gene-explorer/
