RHOF (ras homolog family member F, filopodia associated)

2014-11-01 Affiliation

Identity

HGNC

RHOF

LOCATION

12q24.31

LOCUSID

54509

ALIAS

ARHF,RIF

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 54509
MIM: 618867
HGNC: 15703
Ensembl: ENSG00000139725

Variants:

dbSNP: 54509
ClinVar: 54509
TCGA: ENSG00000139725
COSMIC: RHOF

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000139725	ENST00000267205	Q9HBH0
ENSG00000139725	ENST00000535560	F5GXB1
ENSG00000139725	ENST00000537171	Q9HBH0
ENSG00000139725	ENST00000537265	V9GY67
ENSG00000139725	ENST00000541657	V9GYB3
ENSG00000139725	ENST00000546227	V9GYQ1

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Immune System	REACTOME	R-HSA-168256
Innate Immune System	REACTOME	R-HSA-168249
Signal Transduction	REACTOME	R-HSA-162582
Signaling by Rho GTPases	REACTOME	R-HSA-194315
Rho GTPase cycle	REACTOME	R-HSA-194840
Neutrophil degranulation	REACTOME	R-HSA-6798695

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
25668492	2015	The Rif GTPase regulates cytoskeletal signaling from plexinA4 to promote neurite retraction.	7
25668492	2015	The Rif GTPase regulates cytoskeletal signaling from plexinA4 to promote neurite retraction.	7
22251971	2012	The interplay between the Escherichia coli Rho guanine nucleotide exchange factor effectors and the mammalian RhoGEF inhibitor EspH.	0
22260703	2012	The small Rho GTPase Rif and actin cytoskeletal remodelling.	14
22251971	2012	The interplay between the Escherichia coli Rho guanine nucleotide exchange factor effectors and the mammalian RhoGEF inhibitor EspH.	0
22260703	2012	The small Rho GTPase Rif and actin cytoskeletal remodelling.	14
20233848	2010	The small GTPase Rif is an alternative trigger for the formation of actin stress fibers in epithelial cells.	18
20233848	2010	The small GTPase Rif is an alternative trigger for the formation of actin stress fibers in epithelial cells.	18
18663754	2008	Array-based comparative genomic hybridization in early-stage mycosis fungoides: recurrent deletion of tumor suppressor genes BCL7A, SMAC/DIABLO, and RHOF.	16
18663754	2008	Array-based comparative genomic hybridization in early-stage mycosis fungoides: recurrent deletion of tumor suppressor genes BCL7A, SMAC/DIABLO, and RHOF.	16
11084341	2000	The novel Rho-family GTPase rif regulates coordinated actin-based membrane rearrangements.	33
11084341	2000	The novel Rho-family GTPase rif regulates coordinated actin-based membrane rearrangements.	33

Citation

Dessen P

RHOF (ras homolog family member F, filopodia associated)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/72631/rhof-(ras-homolog-family-member-f-filopodia-associated)