Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6039
MIM: 601981
HGNC: 10048
Ensembl: ENSG00000169413
Variants:
dbSNP: 6039
ClinVar: 6039
TCGA: ENSG00000169413
COSMIC: RNASE6
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000169413 | ENST00000304677 | Q93091 |
| ENSG00000169413 | ENST00000304677 | Q6IB39 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Immune System | REACTOME | R-HSA-168256 |
| Innate Immune System | REACTOME | R-HSA-168249 |
| Antimicrobial peptides | REACTOME | R-HSA-6803157 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37980892 | 2023 | Human Ribonuclease 6 Has a Protective Role during Experimental Urinary Tract Infection. | 2 |
| 37980892 | 2023 | Human Ribonuclease 6 Has a Protective Role during Experimental Urinary Tract Infection. | 2 |
| 35896049 | 2022 | RNASE6 is a novel modifier of APOE-ε4 effects on cognition. | 5 |
| 35896049 | 2022 | RNASE6 is a novel modifier of APOE-ε4 effects on cognition. | 5 |
| 30287244 | 2019 | Characterization of an RNase with two catalytic centers. Human RNase6 catalytic and phosphate-binding site arrangement favors the endonuclease cleavage of polymeric substrates. | 9 |
| 30287244 | 2019 | Characterization of an RNase with two catalytic centers. Human RNase6 catalytic and phosphate-binding site arrangement favors the endonuclease cleavage of polymeric substrates. | 9 |
| 27089320 | 2016 | Insights into the Antimicrobial Mechanism of Action of Human RNase6: Structural Determinants for Bacterial Cell Agglutination and Membrane Permeation. | 23 |
| 27089320 | 2016 | Insights into the Antimicrobial Mechanism of Action of Human RNase6: Structural Determinants for Bacterial Cell Agglutination and Membrane Permeation. | 23 |
| 25075772 | 2015 | Ribonucleases 6 and 7 have antimicrobial function in the human and murine urinary tract. | 51 |
| 25075772 | 2015 | Ribonucleases 6 and 7 have antimicrobial function in the human and murine urinary tract. | 51 |
Citation
Dessen P
RNASE6 (ribonuclease A family member k6)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/72669/rnase6-(ribonuclease-a-family-member-k6)
