RNASE7 (ribonuclease A family member 7)

2014-11-01 Affiliation

Identity

HGNC

RNASE7

LOCATION

14q11.2

LOCUSID

84659

ALIAS

RAE1

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 84659
MIM: 612484
HGNC: 19278
Ensembl: ENSG00000165799

Variants:

dbSNP: 84659
ClinVar: 84659
TCGA: ENSG00000165799
COSMIC: RNASE7

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000165799	ENST00000298690	Q9H1E1
ENSG00000165799	ENST00000481538	Q9H1E1

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Immune System	REACTOME	R-HSA-168256
Innate Immune System	REACTOME	R-HSA-168249
Antimicrobial peptides	REACTOME	R-HSA-6803157

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
35563546	2022	RNase 7 Inhibits Uropathogenic Escherichia coli-Induced Inflammation in Bladder Cells under a High-Glucose Environment by Regulating the JAK/STAT Signaling Pathway.	4
35563546	2022	RNase 7 Inhibits Uropathogenic Escherichia coli-Induced Inflammation in Bladder Cells under a High-Glucose Environment by Regulating the JAK/STAT Signaling Pathway.	4
34779412	2021	Ribonuclease 7 polymorphism rs1263872 reduces antimicrobial activity and associates with pediatric urinary tract infections.	6
34779412	2021	Ribonuclease 7 polymorphism rs1263872 reduces antimicrobial activity and associates with pediatric urinary tract infections.	6
31978413	2020	RNase 7 Promotes Sensing of Self-DNA by Human Keratinocytes and Activates an Antiviral Immune Response.	8
32705284	2020	Involvement of RNase 7 in the malignant potential of oral squamous cell carcinoma cells.	0
31978413	2020	RNase 7 Promotes Sensing of Self-DNA by Human Keratinocytes and Activates an Antiviral Immune Response.	8
32705284	2020	Involvement of RNase 7 in the malignant potential of oral squamous cell carcinoma cells.	0
30814639	2019	RAE1 mediated ZEB1 expression promotes epithelial-mesenchymal transition in breast cancer.	8
31239387	2019	Ribonuclease 7 Shields the Kidney and Bladder from Invasive Uropathogenic Escherichia coli Infection.	24
30814639	2019	RAE1 mediated ZEB1 expression promotes epithelial-mesenchymal transition in breast cancer.	8
31239387	2019	Ribonuclease 7 Shields the Kidney and Bladder from Invasive Uropathogenic Escherichia coli Infection.	24
29157732	2018	RNase 7 Strongly Promotes TLR9-Mediated DNA Sensing by Human Plasmacytoid Dendritic Cells.	23
29346642	2018	RNase 7 but not psoriasin nor sPLA2-IIA associates with Mycobacterium tuberculosis during airway epithelial cell infection.	7
29157732	2018	RNase 7 Strongly Promotes TLR9-Mediated DNA Sensing by Human Plasmacytoid Dendritic Cells.	23

Citation

Dessen P

RNASE7 (ribonuclease A family member 7)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/72670/rnase7-(ribonuclease-a-family-member-7)