Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 246243
MIM: 604123
HGNC: 18466
Ensembl: ENSG00000171865
Variants:
dbSNP: 246243
ClinVar: 246243
TCGA: ENSG00000171865
COSMIC: RNASEH1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000171865 | ENST00000315212 | O60930 |
| ENSG00000171865 | ENST00000315212 | E5KN15 |
| ENSG00000171865 | ENST00000436842 | F8WD93 |
| ENSG00000171865 | ENST00000454734 | F8WBP0 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| DNA replication | KEGG | ko03030 |
| DNA replication | KEGG | hsa03030 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37022517 | 2023 | A pan-cancer analysis of RNASEH1, a potential regulator of the tumor microenvironment. | 2 |
| 37378420 | 2023 | RNase H1 facilitates recombinase recruitment by degrading DNA-RNA hybrids during meiosis. | 1 |
| 37022517 | 2023 | A pan-cancer analysis of RNASEH1, a potential regulator of the tumor microenvironment. | 2 |
| 37378420 | 2023 | RNase H1 facilitates recombinase recruitment by degrading DNA-RNA hybrids during meiosis. | 1 |
| 34348152 | 2021 | BRCA2 deficiency reveals that oxidative stress impairs RNaseH1 function to cripple mitochondrial DNA maintenance. | 14 |
| 34348152 | 2021 | BRCA2 deficiency reveals that oxidative stress impairs RNaseH1 function to cripple mitochondrial DNA maintenance. | 14 |
| 32447804 | 2020 | A non-coding RNASEH1 gene variant associates with type 1 diabetes and interacts with HLA tagSNPs in families from Colombia. | 0 |
| 33396418 | 2020 | Progressive External Ophthalmoplegia in Polish Patients-From Clinical Evaluation to Genetic Confirmation. | 1 |
| 32447804 | 2020 | A non-coding RNASEH1 gene variant associates with type 1 diabetes and interacts with HLA tagSNPs in families from Colombia. | 0 |
| 33396418 | 2020 | Progressive External Ophthalmoplegia in Polish Patients-From Clinical Evaluation to Genetic Confirmation. | 1 |
| 30605451 | 2019 | RNase H1 directs origin-specific initiation of DNA replication in human mitochondria. | 34 |
| 31495875 | 2019 | Kinetic and subcellular analysis of PS-ASO/protein interactions with P54nrb and RNase H1. | 19 |
| 30605451 | 2019 | RNase H1 directs origin-specific initiation of DNA replication in human mitochondria. | 34 |
| 31495875 | 2019 | Kinetic and subcellular analysis of PS-ASO/protein interactions with P54nrb and RNase H1. | 19 |
| 29204916 | 2018 | RNASEH1 gene variants are associated with autoimmune type 1 diabetes in Colombia. | 2 |
Citation
Dessen P
RNASEH1 (ribonuclease H1)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/72673/rnaseh1-(ribonuclease-h1)
