RNF182 (ring finger protein 182)

2014-11-01  

Identity

HGNC
LOCATION
6p23
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 221687
HGNC: 28522
Ensembl: ENSG00000180537

Variants:

dbSNP: 221687
ClinVar: 221687
TCGA: ENSG00000180537
COSMIC: RNF182

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000180537ENST00000420478C9JVS8
ENSG00000180537ENST00000423553C9IZ30
ENSG00000180537ENST00000471906C9JAJ3
ENSG00000180537ENST00000488300Q8N6D2
ENSG00000180537ENST00000488300A0A024QZW5
ENSG00000180537ENST00000488763C9JAK6
ENSG00000180537ENST00000537388Q8N6D2
ENSG00000180537ENST00000537388A0A024QZW5
ENSG00000180537ENST00000537663Q8N6D2
ENSG00000180537ENST00000537663A0A024QZW5
ENSG00000180537ENST00000544682Q8N6D2
ENSG00000180537ENST00000544682A0A024QZW5

Expression (GTEx)

0
5
10
15
20
25

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Class I MHC mediated antigen processing & presentationREACTOMER-HSA-983169
Antigen processing: Ubiquitination & Proteasome degradationREACTOMER-HSA-983168

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
372493012023RNF182 induces p65 ubiquitination to affect PDL1 transcription and suppress immune evasion in lung adenocarcinoma.2
372493012023RNF182 induces p65 ubiquitination to affect PDL1 transcription and suppress immune evasion in lung adenocarcinoma.2
324862212020The Role of Tissue-Specific Ubiquitin Ligases, RNF183, RNF186, RNF182 and RNF152, in Disease and Biological Function.20
324862212020The Role of Tissue-Specific Ubiquitin Ligases, RNF183, RNF186, RNF182 and RNF152, in Disease and Biological Function.20
314325142019The E3 ubiquitin ligase RNF182 inhibits TLR-triggered cytokine production through promoting p65 ubiquitination and degradation.14
314325142019The E3 ubiquitin ligase RNF182 inhibits TLR-triggered cytokine production through promoting p65 ubiquitination and degradation.14

Citation

Dessen P

RNF182 (ring finger protein 182)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/72694/rnf182-(ring-finger-protein-182)