Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 54546
MIM: 617163
HGNC: 25978
Ensembl: ENSG00000178828
Variants:
dbSNP: 54546
ClinVar: 54546
TCGA: ENSG00000178828
COSMIC: RNF186
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000178828 | ENST00000375121 | Q9NXI6 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38160786 | 2024 | Systematic pan-cancer analysis of RNF186 with potential implications in progression and prognosis in human cancer. | 0 |
| 38160786 | 2024 | Systematic pan-cancer analysis of RNF186 with potential implications in progression and prognosis in human cancer. | 0 |
| 34353900 | 2021 | The E3 ubiquitin ligase RNF186 and RNF186 risk variants regulate innate receptor-induced outcomes. | 4 |
| 34623328 | 2021 | Ubiquitination of ATF6 by disease-associated RNF186 promotes the innate receptor-induced unfolded protein response. | 11 |
| 34353900 | 2021 | The E3 ubiquitin ligase RNF186 and RNF186 risk variants regulate innate receptor-induced outcomes. | 4 |
| 34623328 | 2021 | Ubiquitination of ATF6 by disease-associated RNF186 promotes the innate receptor-induced unfolded protein response. | 11 |
| 32486221 | 2020 | The Role of Tissue-Specific Ubiquitin Ligases, RNF183, RNF186, RNF182 and RNF152, in Disease and Biological Function. | 20 |
| 32882406 | 2020 | The role and mechanism of action of RNF186 in colorectal cancer through negative regulation of NF-κB. | 6 |
| 32486221 | 2020 | The Role of Tissue-Specific Ubiquitin Ligases, RNF183, RNF186, RNF182 and RNF152, in Disease and Biological Function. | 20 |
| 32882406 | 2020 | The role and mechanism of action of RNF186 in colorectal cancer through negative regulation of NF-κB. | 6 |
| 31586034 | 2019 | The RING-type E3 ligase RNF186 ubiquitinates Sestrin-2 and thereby controls nutrient sensing. | 13 |
| 31586034 | 2019 | The RING-type E3 ligase RNF186 ubiquitinates Sestrin-2 and thereby controls nutrient sensing. | 13 |
| 27503255 | 2016 | A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis. | 29 |
| 27503255 | 2016 | A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis. | 29 |
| 23511034 | 2013 | Genome-wide association study of ulcerative colitis in Koreans suggests extensive overlapping of genetic susceptibility with Caucasians. | 26 |
Citation
Dessen P
RNF186 (ring finger protein 186)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/72698/rnf186-(ring-finger-protein-186)
