RPP25 (ribonuclease P and MRP subunit p25)

2014-11-01  

Identity

HGNC
LOCATION
15q24.2
LOCUSID
ALIAS
-

Other Information

Locus ID:

NCBI: 54913
HGNC: 30361
Ensembl: ENSG00000178718

Variants:

dbSNP: 54913
ClinVar: 54913
TCGA: ENSG00000178718
COSMIC: RPP25

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000178718ENST00000322177Q9BUL9

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Pathways

PathwaySourceExternal ID
RNA transportKEGGko03013
RNA transportKEGGhsa03013
Ribosome biogenesis in eukaryotesKEGGko03008
Ribosome biogenesis in eukaryotesKEGGhsa03008
Gene ExpressionREACTOMER-HSA-74160
tRNA processingREACTOMER-HSA-72306
tRNA processing in the nucleusREACTOMER-HSA-6784531
rRNA processingREACTOMER-HSA-72312
Major pathway of rRNA processing in the nucleolus and cytosolREACTOMER-HSA-6791226
rRNA processing in the nucleus and cytosolREACTOMER-HSA-8868773

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
335716402021Crystal structure of human RPP20-RPP25 proteins in complex with the P3 domain of lncRNA RMRP.3
335716402021Crystal structure of human RPP20-RPP25 proteins in complex with the P3 domain of lncRNA RMRP.3
319427242020LINC00319 promotes migration, invasion and epithelial-mesenchymal transition process in cervical cancer by regulating miR-3127-5p/RPP25 axis.6
319427242020LINC00319 promotes migration, invasion and epithelial-mesenchymal transition process in cervical cancer by regulating miR-3127-5p/RPP25 axis.6
296251992018Crystal Structure of Human Rpp20/Rpp25 Reveals Quaternary Level Adaptation of the Alba Scaffold as Structural Basis for Single-stranded RNA Binding.0
296251992018Crystal Structure of Human Rpp20/Rpp25 Reveals Quaternary Level Adaptation of the Alba Scaffold as Structural Basis for Single-stranded RNA Binding.0
235870952013Rpp25 is a major target of autoantibodies to the Th/To complex as measured by a novel chemiluminescent assay.9
235870952013Rpp25 is a major target of autoantibodies to the Th/To complex as measured by a novel chemiluminescent assay.9
202154412010Heterodimerization of the human RNase P/MRP subunits Rpp20 and Rpp25 is a prerequisite for interaction with the P3 arm of RNase MRP RNA.24
206323212010RPP25 is developmentally regulated in prefrontal cortex and expressed at decreased levels in autism spectrum disorder.7
202154412010Heterodimerization of the human RNase P/MRP subunits Rpp20 and Rpp25 is a prerequisite for interaction with the P3 arm of RNase MRP RNA.24
206323212010RPP25 is developmentally regulated in prefrontal cortex and expressed at decreased levels in autism spectrum disorder.7

Citation

Dessen P

RPP25 (ribonuclease P and MRP subunit p25)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/72843/rpp25-(ribonuclease-p-and-mrp-subunit-p25)