Identity
HGNC
LOCATION
9p22.1
LOCUSID
ALIAS
FIP-1,FIP1,RAGA
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10670
MIM: 612194
HGNC: 16963
Ensembl: ENSG00000155876
Variants:
dbSNP: 10670
ClinVar: 10670
TCGA: ENSG00000155876
COSMIC: RRAGA
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000155876 | ENST00000380527 | Q7L523 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36697823 | 2023 | Structure of the lysosomal mTORC1-TFEB-Rag-Ragulator megacomplex. | 28 |
| 36823443 | 2023 | RAGA prevents tumor immune evasion of LUAD by promoting CD47 lysosome degradation. | 3 |
| 36697823 | 2023 | Structure of the lysosomal mTORC1-TFEB-Rag-Ragulator megacomplex. | 28 |
| 36823443 | 2023 | RAGA prevents tumor immune evasion of LUAD by promoting CD47 lysosome degradation. | 3 |
| 33340489 | 2021 | Mitochondrial Threonyl-tRNA Synthetase TARS2 Is Required for Threonine-Sensitive mTORC1 Activation. | 19 |
| 34116056 | 2021 | An interdomain hydrogen bond in the Rag GTPases maintains stable mTORC1 signaling in sensing amino acids. | 2 |
| 33340489 | 2021 | Mitochondrial Threonyl-tRNA Synthetase TARS2 Is Required for Threonine-Sensitive mTORC1 Activation. | 19 |
| 34116056 | 2021 | An interdomain hydrogen bond in the Rag GTPases maintains stable mTORC1 signaling in sensing amino acids. | 2 |
| 32100453 | 2020 | C9orf72 associates with inactive Rag GTPases and regulates mTORC1-mediated autophagosomal and lysosomal biogenesis. | 21 |
| 32868926 | 2020 | Structural mechanism for amino acid-dependent Rag GTPase nucleotide state switching by SLC38A9. | 24 |
| 32898476 | 2020 | The Rag GTPase Regulates the Dynamic Behavior of TSC Downstream of Both Amino Acid and Growth Factor Restriction. | 16 |
| 32100453 | 2020 | C9orf72 associates with inactive Rag GTPases and regulates mTORC1-mediated autophagosomal and lysosomal biogenesis. | 21 |
| 32868926 | 2020 | Structural mechanism for amino acid-dependent Rag GTPase nucleotide state switching by SLC38A9. | 24 |
| 32898476 | 2020 | The Rag GTPase Regulates the Dynamic Behavior of TSC Downstream of Both Amino Acid and Growth Factor Restriction. | 16 |
| 30570184 | 2019 | RagA, an mTORC1 activator, interacts with a hedgehog signaling protein, WDR35/IFT121. | 4 |
Citation
Dessen P
RRAGA (Ras related GTP binding A)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/72885/rraga-(ras-related-gtp-binding-a)
