Identity
HGNC
LOCATION
1p34.3
LOCUSID
ALIAS
GTR2,RAGC,TIB929
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 64121
MIM: 608267
HGNC: 19902
Ensembl: ENSG00000116954
Variants:
dbSNP: 64121
ClinVar: 64121
TCGA: ENSG00000116954
COSMIC: RRAGC
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000116954 | ENST00000373001 | Q9HB90 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36697823 | 2023 | Structure of the lysosomal mTORC1-TFEB-Rag-Ragulator megacomplex. | 28 |
| 37057673 | 2023 | De novo missense variants in RRAGC lead to a fatal mTORopathy of early childhood. | 1 |
| 36697823 | 2023 | Structure of the lysosomal mTORC1-TFEB-Rag-Ragulator megacomplex. | 28 |
| 37057673 | 2023 | De novo missense variants in RRAGC lead to a fatal mTORopathy of early childhood. | 1 |
| 33340489 | 2021 | Mitochondrial Threonyl-tRNA Synthetase TARS2 Is Required for Threonine-Sensitive mTORC1 Activation. | 19 |
| 33345445 | 2021 | Cancer-secreted miRNAs regulate amino-acid-induced mTORC1 signaling and fibroblast protein synthesis. | 17 |
| 34071043 | 2021 | TFEB Overexpression, Not mTOR Inhibition, Ameliorates RagC(S75Y) Cardiomyopathy. | 9 |
| 34116056 | 2021 | An interdomain hydrogen bond in the Rag GTPases maintains stable mTORC1 signaling in sensing amino acids. | 2 |
| 34482023 | 2021 | Rag GTPases suppress PRL-3 degradation and predict poor clinical diagnosis of cancer patients with low PRL-3 mRNA expression. | 3 |
| 33340489 | 2021 | Mitochondrial Threonyl-tRNA Synthetase TARS2 Is Required for Threonine-Sensitive mTORC1 Activation. | 19 |
| 33345445 | 2021 | Cancer-secreted miRNAs regulate amino-acid-induced mTORC1 signaling and fibroblast protein synthesis. | 17 |
| 34071043 | 2021 | TFEB Overexpression, Not mTOR Inhibition, Ameliorates RagC(S75Y) Cardiomyopathy. | 9 |
| 34116056 | 2021 | An interdomain hydrogen bond in the Rag GTPases maintains stable mTORC1 signaling in sensing amino acids. | 2 |
| 34482023 | 2021 | Rag GTPases suppress PRL-3 degradation and predict poor clinical diagnosis of cancer patients with low PRL-3 mRNA expression. | 3 |
| 32684241 | 2020 | Euchromatin histone methyltransferase II (EHMT2) regulates the expression of ras-related GTP binding C (RRAGC) protein. | 7 |
Citation
Dessen P
RRAGC (Ras related GTP binding C)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/72886/rragc-(ras-related-gtp-binding-c)
