Identity
HGNC
LOCATION
17p13.3
LOCUSID
ALIAS
SREC,SREC-I,SREC1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8578
MIM: 607873
HGNC: 16820
Ensembl: ENSG00000074660
Variants:
dbSNP: 8578
ClinVar: 8578
TCGA: ENSG00000074660
COSMIC: SCARF1
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Vesicle-mediated transport | REACTOME | R-HSA-5653656 |
| Binding and Uptake of Ligands by Scavenger Receptors | REACTOME | R-HSA-2173782 |
| Scavenging by Class F Receptors | REACTOME | R-HSA-3000484 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35082161 | 2022 | SCARF1-Induced Efferocytosis Plays an Immunomodulatory Role in Humans, and Autoantibodies Targeting SCARF1 Are Produced in Patients with Systemic Lupus Erythematosus. | 4 |
| 35082161 | 2022 | SCARF1-Induced Efferocytosis Plays an Immunomodulatory Role in Humans, and Autoantibodies Targeting SCARF1 Are Produced in Patients with Systemic Lupus Erythematosus. | 4 |
| 34236384 | 2021 | The Role of SREC-Ⅰ in Innate Immunity to Aspergillus fumigatus Keratitis. | 3 |
| 34236384 | 2021 | The Role of SREC-Ⅰ in Innate Immunity to Aspergillus fumigatus Keratitis. | 3 |
| 32296440 | 2020 | Molecular and Cellular Interactions of Scavenger Receptor SR-F1 With Complement C1q Provide Insights Into Its Role in the Clearance of Apoptotic Cells. | 8 |
| 32296440 | 2020 | Molecular and Cellular Interactions of Scavenger Receptor SR-F1 With Complement C1q Provide Insights Into Its Role in the Clearance of Apoptotic Cells. | 8 |
| 29242513 | 2017 | SCARF-1 promotes adhesion of CD4(+) T cells to human hepatic sinusoidal endothelium under conditions of shear stress. | 14 |
| 29242513 | 2017 | SCARF-1 promotes adhesion of CD4(+) T cells to human hepatic sinusoidal endothelium under conditions of shear stress. | 14 |
| 25641411 | 2015 | Scavenger receptor SREC-I promotes double stranded RNA-mediated TLR3 activation in human monocytes. | 16 |
| 25641411 | 2015 | Scavenger receptor SREC-I promotes double stranded RNA-mediated TLR3 activation in human monocytes. | 16 |
| 24788600 | 2014 | A nasal epithelial receptor for Staphylococcus aureus WTA governs adhesion to epithelial cells and modulates nasal colonization. | 41 |
| 25155057 | 2014 | Hsp90-peptide complexes stimulate antigen presentation through the class II pathway after binding scavenger receptor SREC-I. | 20 |
| 24788600 | 2014 | A nasal epithelial receptor for Staphylococcus aureus WTA governs adhesion to epithelial cells and modulates nasal colonization. | 41 |
| 25155057 | 2014 | Hsp90-peptide complexes stimulate antigen presentation through the class II pathway after binding scavenger receptor SREC-I. | 20 |
| 21190681 | 2011 | The zymogen granule protein 2 (GP2) binds to scavenger receptor expressed on endothelial cells I (SREC-I). | 19 |
Citation
Dessen P
SCARF1 (scavenger receptor class F member 1)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/73003/scarf1-(scavenger-receptor-class-f-member-1)
