Identity
HGNC
LOCATION
3p22.2
LOCUSID
ALIAS
FEPS3,HSAN7,NAV1.9,NaN,PN5,SCN12A,SNS-2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 11280
MIM: 604385
HGNC: 10583
Ensembl: ENSG00000168356
Variants:
dbSNP: 11280
ClinVar: 11280
TCGA: ENSG00000168356
COSMIC: SCN11A
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000168356 | ENST00000302328 | Q9UI33 |
| ENSG00000168356 | ENST00000444237 | Q9UI33 |
| ENSG00000168356 | ENST00000456224 | Q9UI33 |
| ENSG00000168356 | ENST00000668754 | Q9UI33 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38734669 | 2024 | Elevated SCN11A concentrations associated with lower serum lipid levels in patients with major depressive disorder. | 0 |
| 38734669 | 2024 | Elevated SCN11A concentrations associated with lower serum lipid levels in patients with major depressive disorder. | 0 |
| 37061202 | 2023 | Understanding the physiological role of Na(V)1.9: Challenges and opportunities for pain modulation. | 1 |
| 37186898 | 2023 | The influence of Nav1.9 channels on intestinal hyperpathia and dysmotility. | 1 |
| 37061202 | 2023 | Understanding the physiological role of Na(V)1.9: Challenges and opportunities for pain modulation. | 1 |
| 37186898 | 2023 | The influence of Nav1.9 channels on intestinal hyperpathia and dysmotility. | 1 |
| 34930944 | 2021 | Contributions of Na(V)1.8 and Na(V)1.9 to excitability in human induced pluripotent stem-cell derived somatosensory neurons. | 4 |
| 34930944 | 2021 | Contributions of Na(V)1.8 and Na(V)1.9 to excitability in human induced pluripotent stem-cell derived somatosensory neurons. | 4 |
| 31822564 | 2020 | A 49-residue sequence motif in the C terminus of Nav1.9 regulates trafficking of the channel to the plasma membrane. | 6 |
| 32132394 | 2020 | Alcohol-aggravated episodic pain in humans with SCN11A mutation and ALDH2 polymorphism. | 5 |
| 32601768 | 2020 | Painful and painless mutations of SCN9A and SCN11A voltage-gated sodium channels. | 15 |
| 31822564 | 2020 | A 49-residue sequence motif in the C terminus of Nav1.9 regulates trafficking of the channel to the plasma membrane. | 6 |
| 32132394 | 2020 | Alcohol-aggravated episodic pain in humans with SCN11A mutation and ALDH2 polymorphism. | 5 |
| 32601768 | 2020 | Painful and painless mutations of SCN9A and SCN11A voltage-gated sodium channels. | 15 |
| 30554136 | 2019 | Yield of peripheral sodium channels gene screening in pure small fibre neuropathy. | 28 |
Citation
Dessen P
SCN11A (sodium voltage-gated channel alpha subunit 11)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/73044/scn11a-(sodium-voltage-gated-channel-alpha-subunit-11)
