Identity
HGNC
LOCATION
2q24.3
LOCUSID
ALIAS
DEE62,EIEE62,FFEVF4,NAC3,Nav1.3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6328
MIM: 182391
HGNC: 10590
Ensembl: ENSG00000153253
Variants:
dbSNP: 6328
ClinVar: 6328
TCGA: ENSG00000153253
COSMIC: SCN3A
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37935051 | 2024 | Targeted blockade of aberrant sodium current in a stem cell-derived neuron model of SCN3A encephalopathy. | 0 |
| 38568055 | 2024 | Neurodevelopmental disorder in a patient with HMBS and SCN3A variants-A possibly blended phenotype further delineating autosomal recessive HMBS related disease. | 0 |
| 37935051 | 2024 | Targeted blockade of aberrant sodium current in a stem cell-derived neuron model of SCN3A encephalopathy. | 0 |
| 38568055 | 2024 | Neurodevelopmental disorder in a patient with HMBS and SCN3A variants-A possibly blended phenotype further delineating autosomal recessive HMBS related disease. | 0 |
| 35801810 | 2022 | Association of sodium voltage-gated channel genes polymorphisms with epilepsy risk and prognosis in the Saudi population. | 1 |
| 35801810 | 2022 | Association of sodium voltage-gated channel genes polymorphisms with epilepsy risk and prognosis in the Saudi population. | 1 |
| 33895391 | 2021 | Mutations in the sodium channel genes SCN1A, SCN3A, and SCN9A in children with epilepsy with febrile seizures plus(EFS+). | 3 |
| 33895391 | 2021 | Mutations in the sodium channel genes SCN1A, SCN3A, and SCN9A in children with epilepsy with febrile seizures plus(EFS+). | 3 |
| 32515017 | 2020 | SCN3A-Related Neurodevelopmental Disorder: A Spectrum of Epilepsy and Brain Malformation. | 21 |
| 32515017 | 2020 | SCN3A-Related Neurodevelopmental Disorder: A Spectrum of Epilepsy and Brain Malformation. | 21 |
| 30993766 | 2019 | Long noncoding RNA HOXA-AS2 regulates the expression of SCN3A by sponging miR-106a in breast cancer. | 22 |
| 30993766 | 2019 | Long noncoding RNA HOXA-AS2 regulates the expression of SCN3A by sponging miR-106a in breast cancer. | 22 |
| 29466837 | 2018 | Mutations in SCN3A cause early infantile epileptic encephalopathy. | 36 |
| 29578003 | 2018 | Abnormal changes in voltage-gated sodium channels subtypes Na(V)1.1, Na(V)1.2, Na(V)1.3, Na(V)1.6 and CaM/CaMKII pathway in low-grade astrocytoma. | 4 |
| 30146301 | 2018 | Sodium Channel SCN3A (Na(V)1.3) Regulation of Human Cerebral Cortical Folding and Oral Motor Development. | 59 |
Citation
Dessen P
SCN3A (sodium voltage-gated channel alpha subunit 3)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/73048/scn3a-(sodium-voltage-gated-channel-alpha-subunit-3)
