SCOC (short coiled-coil protein)

2014-11-01  

Identity

HGNC
LOCATION
4q31.1
LOCUSID
ALIAS
HRIHFB2072,SCOCO,UNC-69
FUSION GENES

Other Information

Locus ID:

NCBI: 60592
HGNC: 20335
Ensembl: ENSG00000153130

Variants:

dbSNP: 60592
ClinVar: 60592
TCGA: ENSG00000153130
COSMIC: SCOC

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000153130ENST00000338517Q9UIL1
ENSG00000153130ENST00000394201A0A0C4DGB0
ENSG00000153130ENST00000394203Q9UIL1
ENSG00000153130ENST00000394205Q9UIL1
ENSG00000153130ENST00000502535A0A0C4DGB0
ENSG00000153130ENST00000506322A0A0C4DGB0
ENSG00000153130ENST00000506597Q9UIL1
ENSG00000153130ENST00000510586A0A0C4DGB0
ENSG00000153130ENST00000512749A0A0C4DGB0
ENSG00000153130ENST00000608372Q9UIL1
ENSG00000153130ENST00000614192Q9UIL1

Expression (GTEx)

0
10
20
30
40
50
60
70

Pathways

PathwaySourceExternal ID
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
Intra-Golgi and retrograde Golgi-to-ER trafficREACTOMER-HSA-6811442
Retrograde transport at the Trans-Golgi-NetworkREACTOMER-HSA-6811440

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
338450852021Phosphorylation of the LIR Domain of SCOC Modulates ATG8 Binding Affinity and Specificity.10
338450852021Phosphorylation of the LIR Domain of SCOC Modulates ATG8 Binding Affinity and Specificity.10
270231752016Genome-wide association study of lifetime cannabis use based on a large meta-analytic sample of 32 330 subjects from the International Cannabis Consortium.93
270231752016Genome-wide association study of lifetime cannabis use based on a large meta-analytic sample of 32 330 subjects from the International Cannabis Consortium.93
240984812013Crystal structure of the human short coiled coil protein and insights into SCOC-FEZ1 complex formation.4
241161252013Structural analysis of intermolecular interactions in the kinesin adaptor complex fasciculation and elongation protein zeta 1/ short coiled-coil protein (FEZ1/SCOCO).4
240984812013Crystal structure of the human short coiled coil protein and insights into SCOC-FEZ1 complex formation.4
241161252013Structural analysis of intermolecular interactions in the kinesin adaptor complex fasciculation and elongation protein zeta 1/ short coiled-coil protein (FEZ1/SCOCO).4
223540372012Genome-wide siRNA screen reveals amino acid starvation-induced autophagy requires SCOC and WAC.62
223540372012Genome-wide siRNA screen reveals amino acid starvation-induced autophagy requires SCOC and WAC.62
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78

Citation

Dessen P

SCOC (short coiled-coil protein)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/73052/scoc-(short-coiled-coil-protein)