Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 89777
MIM: 615662
HGNC: 14220
Ensembl: ENSG00000166634
Variants:
dbSNP: 89777
ClinVar: 89777
TCGA: ENSG00000166634
COSMIC: SERPINB12
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000166634 | ENST00000269491 | Q96P63 |
| ENSG00000166634 | ENST00000382768 | Q96P63 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Immune System | REACTOME | R-HSA-168256 |
| Innate Immune System | REACTOME | R-HSA-168249 |
| Neutrophil degranulation | REACTOME | R-HSA-6798695 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38504347 | 2024 | Smoking behavior associated upregulation of SERPINB12 promotes proliferation and metastasis via activating WNT signaling in NSCLC. | 0 |
| 38504347 | 2024 | Smoking behavior associated upregulation of SERPINB12 promotes proliferation and metastasis via activating WNT signaling in NSCLC. | 0 |
| 31653522 | 2020 | SERPINB12 as a possible marker of steroid dependency in children with eosinophilic esophagitis: A pilot study. | 0 |
| 31653522 | 2020 | SERPINB12 as a possible marker of steroid dependency in children with eosinophilic esophagitis: A pilot study. | 0 |
| 31026779 | 2019 | Deciphering the three-domain architecture in schlafens and the structures and roles of human schlafen12 and serpinB12 in transcriptional regulation. | 10 |
| 31026779 | 2019 | Deciphering the three-domain architecture in schlafens and the structures and roles of human schlafen12 and serpinB12 in transcriptional regulation. | 10 |
| 30045019 | 2018 | Schlafen 12 Interaction with SerpinB12 and Deubiquitylases Drives Human Enterocyte Differentiation. | 24 |
| 30045019 | 2018 | Schlafen 12 Interaction with SerpinB12 and Deubiquitylases Drives Human Enterocyte Differentiation. | 24 |
| 26220980 | 2015 | Human SERPINB12 Is an Abundant Intracellular Serpin Expressed in Most Surface and Glandular Epithelia. | 12 |
| 26497600 | 2015 | SERPINB12 Is a Slow-Binding Inhibitor of Granzyme A and Hepsin. | 6 |
| 26220980 | 2015 | Human SERPINB12 Is an Abundant Intracellular Serpin Expressed in Most Surface and Glandular Epithelia. | 12 |
| 26497600 | 2015 | SERPINB12 Is a Slow-Binding Inhibitor of Granzyme A and Hepsin. | 6 |
Citation
Dessen P
SERPINB12 (serpin family B member 12)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/73145/
