Identity
HGNC
LOCATION
21q22.12
LOCUSID
ALIAS
C21orf18,C21orf27
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 54093
HGNC: 1258
Ensembl: ENSG00000185917
Variants:
dbSNP: 54093
ClinVar: 54093
TCGA: ENSG00000185917
COSMIC: SETD4
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA449212 | daunorubicin | Chemical | VariantAnnotation | associated | PK | 19204081 | |
| PA449412 | doxorubicin | Chemical | VariantAnnotation | associated | PK | 19204081 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37879429 | 2023 | SETD4 inhibits prostate cancer development by promoting H3K27me3-mediated NUPR1 transcriptional repression and cell cycle arrest. | 0 |
| 37879429 | 2023 | SETD4 inhibits prostate cancer development by promoting H3K27me3-mediated NUPR1 transcriptional repression and cell cycle arrest. | 0 |
| 31308046 | 2019 | SET Domain-Containing Protein 4 Epigenetically Controls Breast Cancer Stem Cell Quiescence. | 27 |
| 31308046 | 2019 | SET Domain-Containing Protein 4 Epigenetically Controls Breast Cancer Stem Cell Quiescence. | 27 |
Citation
Dessen P
SETD4 (SET domain containing 4)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/73155/setd4-(set-domain-containing-4)
