SFXN1 (sideroflexin 1)

2014-11-01  

Identity

HGNC
LOCATION
5q35.2
LOCUSID
ALIAS
SLC56A1,TCC
FUSION GENES

Other Information

Locus ID:

NCBI: 94081
MIM: 615569
HGNC: 16085
Ensembl: ENSG00000164466

Variants:

dbSNP: 94081
ClinVar: 94081
TCGA: ENSG00000164466
COSMIC: SFXN1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000164466ENST00000321442Q9H9B4
ENSG00000164466ENST00000502393S4R2X2
ENSG00000164466ENST00000502865H0Y9J5
ENSG00000164466ENST00000506963D6RFI0
ENSG00000164466ENST00000507017D6RDG7
ENSG00000164466ENST00000507823D6RAE9

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
382337522024Comprehensive analysis the prognostic and immune characteristics of mitochondrial transport-related gene SFXN1 in lung adenocarcinoma.1
385375392024SFXN1-mediated immune cell infiltration and tumorigenesis in lung adenocarcinoma: A potential therapeutic target.0
382337522024Comprehensive analysis the prognostic and immune characteristics of mitochondrial transport-related gene SFXN1 in lung adenocarcinoma.1
385375392024SFXN1-mediated immune cell infiltration and tumorigenesis in lung adenocarcinoma: A potential therapeutic target.0
372962282023Loss of SFXN1 mitigates lipotoxicity and predicts poor outcome in non-viral hepatocellular carcinoma.0
372962282023Loss of SFXN1 mitigates lipotoxicity and predicts poor outcome in non-viral hepatocellular carcinoma.0
358785322022Overexpression of SFXN1 indicates poor prognosis and promotes tumor progression in lung adenocarcinoma.5
358785322022Overexpression of SFXN1 indicates poor prognosis and promotes tumor progression in lung adenocarcinoma.5
337305812021The mitochondrial carrier SFXN1 is critical for complex III integrity and cellular metabolism.23
337305812021The mitochondrial carrier SFXN1 is critical for complex III integrity and cellular metabolism.23
329509192020CircSFXN1 regulates the behaviour of trophoblasts and likely mediates preeclampsia.11
329509192020CircSFXN1 regulates the behaviour of trophoblasts and likely mediates preeclampsia.11
304427782018SFXN1 is a mitochondrial serine transporter required for one-carbon metabolism.97
304427782018SFXN1 is a mitochondrial serine transporter required for one-carbon metabolism.97
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20

Citation

Dessen P

SFXN1 (sideroflexin 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/73173/sfxn1-(sideroflexin-1)