SGIP1 (SH3GL interacting endocytic adaptor 1)

2014-11-01  

Identity

HGNC
LOCATION
1p31.3
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 84251
MIM: 611540
HGNC: 25412
Ensembl: ENSG00000118473

Variants:

dbSNP: 84251
ClinVar: 84251
TCGA: ENSG00000118473
COSMIC: SGIP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000118473ENST00000237247Q9BQI5
ENSG00000118473ENST00000371037Q9BQI5
ENSG00000118473ENST00000371039Q9BQI5
ENSG00000118473ENST00000424320F6R8P8
ENSG00000118473ENST00000435165Q6ZV33

Expression (GTEx)

0
5
10
15
20
25

Pathways

PathwaySourceExternal ID
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
Clathrin-mediated endocytosisREACTOMER-HSA-8856828
Cargo recognition for clathrin-mediated endocytosisREACTOMER-HSA-8856825

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
331188322021Plasma SGIP1 methylation in diagnosis and prognosis prediction in hepatocellular carcinoma.2
331188322021Plasma SGIP1 methylation in diagnosis and prognosis prediction in hepatocellular carcinoma.2
302369862018SGIP1 dimerizes via intermolecular disulfide bond in μHD domain during cellular endocytosis.3
302369862018SGIP1 dimerizes via intermolecular disulfide bond in μHD domain during cellular endocytosis.3
268225362016Structural basis for the recognition of two consecutive mutually interacting DPF motifs by the SGIP1 μ homology domain.10
280309332016Event-related potentials (ERP) and SGIP1 gene polymorphisms in alcoholics: relation to family history of alcoholism and drug usage.7
268225362016Structural basis for the recognition of two consecutive mutually interacting DPF motifs by the SGIP1 μ homology domain.10
280309332016Event-related potentials (ERP) and SGIP1 gene polymorphisms in alcoholics: relation to family history of alcoholism and drug usage.7
214071712012Genetic variation in SH3-domain GRB2-like (endophilin)-interacting protein 1 has a major impact on fat mass.12
214071712012Genetic variation in SH3-domain GRB2-like (endophilin)-interacting protein 1 has a major impact on fat mass.12
213176822011Nonreplication of an association of SGIP1 SNPs with alcohol dependence and resting theta EEG power.5
213176822011Nonreplication of an association of SGIP1 SNPs with alcohol dependence and resting theta EEG power.5
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
204214872010Genome-wide association identifies candidate genes that influence the human electroencephalogram.38
209468752010Intersectin 1 forms complexes with SGIP1 and Reps1 in clathrin-coated pits.19

Citation

Dessen P

SGIP1 (SH3GL interacting endocytic adaptor 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/73182/sgip1-(sh3gl-interacting-endocytic-adaptor-1)