SH3TC2 (SH3 domain and tetratricopeptide repeats 2)

2014-11-01  

Identity

HGNC
LOCATION
5q32
LOCUSID
ALIAS
CMT4C,MNMN
FUSION GENES

Other Information

Locus ID:

NCBI: 79628
MIM: 608206
HGNC: 29427
Ensembl: ENSG00000169247

Variants:

dbSNP: 79628
ClinVar: 79628
TCGA: ENSG00000169247
COSMIC: SH3TC2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000169247ENST00000323829D6RA65
ENSG00000169247ENST00000502274Q8TF17
ENSG00000169247ENST00000504517H0Y8Q9
ENSG00000169247ENST00000504690E9PDF1
ENSG00000169247ENST00000510779H0Y9E7
ENSG00000169247ENST00000511307D6RFX2
ENSG00000169247ENST00000512049Q8TF17
ENSG00000169247ENST00000513604D6RA65
ENSG00000169247ENST00000515425Q8TF17
ENSG00000169247ENST00000515425A0A514TP98
ENSG00000169247ENST00000643113A0A2R8YCS9

Expression (GTEx)

0
5
10
15

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
373729332023Evaluation of Pathogenicity and Causativity of Variants in the MPZ and SH3TC2 Genes in a Family Case of Hereditary Peripheral Neuropathy.1
379294312023Characterisation of Patients with SH3TC2 Associated Neuropathy in an Indian Cohort.1
373729332023Evaluation of Pathogenicity and Causativity of Variants in the MPZ and SH3TC2 Genes in a Family Case of Hereditary Peripheral Neuropathy.1
379294312023Characterisation of Patients with SH3TC2 Associated Neuropathy in an Indian Cohort.1
335872402022Screening for SH3TC2 variants in Charcot-Marie-Tooth disease in a cohort of Chinese patients.4
335872402022Screening for SH3TC2 variants in Charcot-Marie-Tooth disease in a cohort of Chinese patients.4
306537842019Mutational screening of the SH3TC2 gene in Greek patients with suspected demyelinating recessive Charcot-Marie-Tooth disease reveals a varied and unusual phenotypic spectrum.4
312277902019Compound heterozygous mutations of SH3TC2 in Charcot-Marie-Tooth disease type 4C patients.5
316347152019Implication of the SH3TC2 gene in Charcot-Marie-Tooth disease associated with deafness and/or scoliosis: Illustration with four new pathogenic variants.7
306537842019Mutational screening of the SH3TC2 gene in Greek patients with suspected demyelinating recessive Charcot-Marie-Tooth disease reveals a varied and unusual phenotypic spectrum.4
312277902019Compound heterozygous mutations of SH3TC2 in Charcot-Marie-Tooth disease type 4C patients.5
316347152019Implication of the SH3TC2 gene in Charcot-Marie-Tooth disease associated with deafness and/or scoliosis: Illustration with four new pathogenic variants.7
289819552018Charcot-Marie-Tooth Disease type 4C: Novel mutations, clinical presentations, and diagnostic challenges.6
293363622018Screening for SH3TC2, PMP2, and BSCL2 Variants in a Cohort of Chinese Patients with Charcot-Marie-Tooth.2
289819552018Charcot-Marie-Tooth Disease type 4C: Novel mutations, clinical presentations, and diagnostic challenges.6

Citation

Dessen P

SH3TC2 (SH3 domain and tetratricopeptide repeats 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/73216/sh3tc2-(sh3-domain-and-tetratricopeptide-repeats-2)