Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
Variants:
dbSNP: 400709
ClinVar: 400709
COSMIC: SIGLEC16
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Immune System | REACTOME | R-HSA-168256 |
| Innate Immune System | REACTOME | R-HSA-168249 |
| DAP12 interactions | REACTOME | R-HSA-2172127 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37058255 | 2023 | Proinflammatory Macrophage Activation by the Polysialic Acid-Siglec-16 Axis Is Linked to Increased Survival of Patients with Glioblastoma. | 2 |
| 37058255 | 2023 | Proinflammatory Macrophage Activation by the Polysialic Acid-Siglec-16 Axis Is Linked to Increased Survival of Patients with Glioblastoma. | 2 |
| 28100677 | 2017 | Paired Siglec receptors generate opposite inflammatory responses to a human-specific pathogen. | 37 |
| 28100677 | 2017 | Paired Siglec receptors generate opposite inflammatory responses to a human-specific pathogen. | 37 |
| 18629938 | 2008 | SIGLEC16 encodes a DAP12-associated receptor expressed in macrophages that evolved from its inhibitory counterpart SIGLEC11 and has functional and non-functional alleles in humans. | 51 |
| 18629938 | 2008 | SIGLEC16 encodes a DAP12-associated receptor expressed in macrophages that evolved from its inhibitory counterpart SIGLEC11 and has functional and non-functional alleles in humans. | 51 |
Citation
Dessen P
SIGLEC16 (sialic acid binding Ig like lectin 16)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/73245/siglec16-(sialic-acid-binding-ig-like-lectin-16)
