Identity
HGNC
LOCATION
12q24.33
LOCUSID
ALIAS
FP12591,PHT1,PTR4
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 121260
MIM: 615806
HGNC: 23090
Ensembl: ENSG00000139370
Variants:
dbSNP: 121260
ClinVar: 121260
TCGA: ENSG00000139370
COSMIC: SLC15A4
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000139370 | ENST00000266771 | Q8N697 |
| ENSG00000139370 | ENST00000376740 | B6ZDF2 |
| ENSG00000139370 | ENST00000376744 | H7BYB7 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37610621 | 2023 | Oligopeptide/Histidine Transporter PHT1 and PHT2 - Function, Regulation, and Pathophysiological Implications Specifically in Immunoregulation. | 2 |
| 37863876 | 2023 | A conformation-locking inhibitor of SLC15A4 with TASL proteostatic anti-inflammatory activity. | 2 |
| 37863913 | 2023 | Structural basis for recruitment of TASL by SLC15A4 in human endolysosomal TLR signaling. | 2 |
| 37610621 | 2023 | Oligopeptide/Histidine Transporter PHT1 and PHT2 - Function, Regulation, and Pathophysiological Implications Specifically in Immunoregulation. | 2 |
| 37863876 | 2023 | A conformation-locking inhibitor of SLC15A4 with TASL proteostatic anti-inflammatory activity. | 2 |
| 37863913 | 2023 | Structural basis for recruitment of TASL by SLC15A4 in human endolysosomal TLR signaling. | 2 |
| 35562597 | 2022 | Whole exome sequencing identifies novel germline variants of SLC15A4 gene as potentially cancer predisposing in familial colorectal cancer. | 0 |
| 36361959 | 2022 | Identification of SLC15A4/PHT1 Gene Products Upregulation Marking the Intestinal Epithelial Monolayer of Ulcerative Colitis Patients. | 0 |
| 35562597 | 2022 | Whole exome sequencing identifies novel germline variants of SLC15A4 gene as potentially cancer predisposing in familial colorectal cancer. | 0 |
| 36361959 | 2022 | Identification of SLC15A4/PHT1 Gene Products Upregulation Marking the Intestinal Epithelial Monolayer of Ulcerative Colitis Patients. | 0 |
| 33560415 | 2021 | Human SLC15A4 is crucial for TLR-mediated type I interferon production and mitochondrial integrity. | 16 |
| 33560415 | 2021 | Human SLC15A4 is crucial for TLR-mediated type I interferon production and mitochondrial integrity. | 16 |
| 32433612 | 2020 | TASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7-9. | 74 |
| 32433612 | 2020 | TASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7-9. | 74 |
| 31073693 | 2019 | The proton-coupled oligopeptide transporters PEPT2, PHT1 and PHT2 mediate the uptake of carnosine in glioblastoma cells. | 17 |
Citation
Dessen P
SLC15A4 (solute carrier family 15 member 4)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/73286/slc15a4-(solute-carrier-family-15-member-4)
